CancerFax
PRECISION ONCOLOGY

NGS VS SINGLE
GENE TESTING

When tumour is tested one gene at a time, a patient with lung cancer might never have their ROS1 fusion identified -- because nobody ordered that specific test. Comprehensive NGS finds what is there, not just what was looked for.

Reviewed by: CancerFax Medical Team, Oncology & Haematology SpecialistsLast reviewed: April 16, 20268 min read

Comprehensive NGS vs Sequential Single-Gene Testing

Comprehensive NGS

  • 300-500+ genes in one test from one tissue sample
  • TMB and MSI included automatically
  • Unexpected findings identified regardless of what was suspected
  • One 2-3 week wait for complete molecular picture

Sequential Single-Gene Tests

  • One gene answered per test; multiple rounds needed for full picture
  • TMB and MSI require separate orders
  • Only finds what was specifically requested
  • Sequential waits can take months; tissue use multiplies

Frequently Asked Questions

    How CancerFax Helps

    CancerFax is a specialist cancer access and patient-navigation platform. We help patients and families understand their options, organise medical records, coordinate hospital communication, and support cross-border treatment planning where appropriate.

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    Medical Record Review

    We help collect and organise reports, scans, pathology, biomarker results, and treatment history for structured case review.

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    Eligibility Coordination

    We communicate with hospitals or trial teams to assess whether a case may be suitable for further screening.

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    Hospital Communication

    We support appointment coordination, document submission, translation, and direct communication with international departments.

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    Travel & Admission Support

    For international patients, we help with practical coordination — travel planning, hospital admission guidance, and local support.

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    Treatment & Trial Navigation

    If this option is not suitable, we help explore other relevant treatments, clinical trials, or advanced care pathways.

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    End-to-end Coordination

    From inquiry through to follow-up, our coordinators provide a single point of contact for the family.

    CancerFax does not guarantee treatment access, eligibility, or clinical outcome. Our role is to help patients access accurate information, structured review, and appropriate specialist pathways.

    Questions About Which Testing Approach Is Right for Your Situation?

    CancerFax helps patients understand what type of molecular testing has been done and whether comprehensive NGS adds clinically relevant information for their specific cancer.

    This content is for informational purposes only and does not constitute medical advice. Always consult a qualified oncologist before making treatment decisions.