CancerFax
PRECISION ONCOLOGY

MSI TESTING
EXPLAINED

MSI-H is the molecular feature that produces the most dramatic treatment consequence per positive result. Any cancer type. Any organ. If MSI-H, pembrolizumab is approved -- the first-ever tumour-agnostic drug approval in oncology history.

Reviewed by: CancerFax Medical Team, Oncology & Haematology SpecialistsLast reviewed: April 16, 20268 min read

MSI-H Clinical Significance at a Glance

  • 2017Year of first tumour-agnostic cancer drug approval (pembrolizumab for MSI-H)
  • 5%Approximate prevalence of MSI-H in metastatic colorectal cancer
  • 20-30%Prevalence of MSI-H/dMMR in endometrial cancer

Frequently Asked Questions

    How CancerFax Helps

    CancerFax is a specialist cancer access and patient-navigation platform. We help patients and families understand their options, organise medical records, coordinate hospital communication, and support cross-border treatment planning where appropriate.

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    Medical Record Review

    We help collect and organise reports, scans, pathology, biomarker results, and treatment history for structured case review.

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    Eligibility Coordination

    We communicate with hospitals or trial teams to assess whether a case may be suitable for further screening.

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    Hospital Communication

    We support appointment coordination, document submission, translation, and direct communication with international departments.

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    Travel & Admission Support

    For international patients, we help with practical coordination — travel planning, hospital admission guidance, and local support.

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    Treatment & Trial Navigation

    If this option is not suitable, we help explore other relevant treatments, clinical trials, or advanced care pathways.

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    End-to-end Coordination

    From inquiry through to follow-up, our coordinators provide a single point of contact for the family.

    CancerFax does not guarantee treatment access, eligibility, or clinical outcome. Our role is to help patients access accurate information, structured review, and appropriate specialist pathways.

    Questions About MSI Status and Immunotherapy Eligibility?

    CancerFax reviews your MSI, TMB, and PD-L1 results together to assess the complete immunotherapy eligibility picture for your specific cancer.

    This content is for informational purposes only and does not constitute medical advice. Always consult a qualified oncologist before making treatment decisions.