HOW GENOMIC TESTING GUIDES
CANCER TREATMENT
Understanding how next-generation sequencing, biomarker panels, and liquid biopsies help oncologists match patients to the most effective precision therapies.
The Foundation of Precision Oncology
Genomic testing reveals the molecular blueprint of a patient's tumor. By identifying specific mutations, gene fusions, and biomarkers, oncologists can select therapies proven to work against those exact targets.
βGenomic testing transforms cancer treatment from guesswork to precision.β
Types of Genomic Tests for Cancer
Next-Generation Sequencing (NGS)
Analyzes hundreds of cancer-related genes simultaneously from tumor tissue. Standard panels include FoundationOne CDx and Tempus xT.
Liquid Biopsy (ctDNA)
Detects tumor DNA fragments circulating in blood. Non-invasive alternative when tissue biopsy is difficult. Guardant360 and FoundationOne Liquid CDx.
IHC & FISH
Immunohistochemistry and fluorescence in-situ hybridization detect specific proteins or gene amplifications (HER2, PD-L1, ALK).
MSI / TMB Testing
Microsatellite instability and tumor mutational burden predict immunotherapy response across cancer types.
Key Biomarkers and Their Matched Treatments
| Biomarker | Cancer Types | Matched Treatment |
|---|---|---|
| EGFR mutation | NSCLC | Osimertinib, erlotinib |
| HER2 amplification | Breast, gastric | Trastuzumab, T-DXd |
| BRAF V600E | Melanoma, CRC, NSCLC | Dabrafenib + trametinib |
| ALK fusion | NSCLC | Alectinib, lorlatinib |
| PD-L1 high (>50%) | Multiple | Pembrolizumab monotherapy |
| MSI-H / dMMR | Tumor-agnostic | Pembrolizumab |
| BRCA1/2 mutation | Breast, ovarian, prostate | Olaparib, niraparib |
Frequently Asked Questions
About Genomic Testing
How CancerFax Helps
CancerFax is a specialist cancer access and patient-navigation platform. We help patients and families understand their options, organise medical records, coordinate hospital communication, and support cross-border treatment planning where appropriate.
We help collect and organise reports, scans, pathology, biomarker results, and treatment history for structured case review.
We communicate with hospitals or trial teams to assess whether a case may be suitable for further screening.
We support appointment coordination, document submission, translation, and direct communication with international departments.
For international patients, we help with practical coordination β travel planning, hospital admission guidance, and local support.
If this option is not suitable, we help explore other relevant treatments, clinical trials, or advanced care pathways.
From inquiry through to follow-up, our coordinators provide a single point of contact for the family.
CancerFax does not guarantee treatment access, eligibility, or clinical outcome. Our role is to help patients access accurate information, structured review, and appropriate specialist pathways.
Need Help with Genomic Testing and Treatment Matching?
Upload your reports and our team will help interpret genomic results and identify matched treatment options.
This content is for informational purposes only and does not constitute medical advice. Always consult a qualified oncologist before making treatment decisions.