CancerFax
PRE-TREATMENT GUIDE

TESTS REQUIRED BEFORE
ADVANCED THERAPY

A complete guide to diagnostic and eligibility tests required before starting immunotherapy, CAR-T, targeted therapy, or other advanced cancer treatments.

Reviewed by: CancerFax Medical Team, Oncology & Haematology SpecialistsLast reviewed: April 16, 20269 min read

Why Pre-Treatment Testing Matters

Advanced cancer therapies require thorough evaluation before initiation. These tests confirm eligibility, identify potential risks, establish baselines for monitoring, and ensure the selected treatment is safe and appropriate.

Universal Pre-Treatment Tests

These tests are required regardless of which advanced therapy is planned.

TestPurposeTurnaround
Complete Blood Count (CBC)Assess blood cell levels and bone marrow functionSame day
Comprehensive Metabolic PanelLiver and kidney function assessmentSame day
PET-CT or CT ImagingDisease staging and treatment response baseline1-3 days
Pathology / Biopsy ReviewConfirm diagnosis and histologyAlready available
Echocardiogram (ECHO)Cardiac function (LVEF) baselineSame day
Pulmonary Function TestsLung capacity assessmentSame day
Infectious Disease PanelHIV, HBV, HCV screening1-3 days

Therapy-Specific Test Requirements

  • Before CAR-T Therapy

    Leukapheresis feasibility, absolute lymphocyte count, cardiac LVEF >40%, no active infections, adequate organ function.

  • Before Immunotherapy

    PD-L1 IHC, MSI/dMMR testing, TMB if applicable, thyroid function baseline, autoimmune disease screening.

  • Before Targeted Therapy

    NGS/genomic profiling for actionable mutations, relevant IHC/FISH confirmation, baseline organ function.

  • Before TIL Therapy

    Resectable tumor for TIL harvest, adequate performance status (ECOG 0-1), cardiac and pulmonary clearance.

Typical Pre-Treatment Testing Timeline

  1. 1

    Medical Records Review

    Compile existing pathology, imaging, and treatment history.

  2. 2

    Blood Work & Labs

    CBC, CMP, infectious disease panel, tumor markers.

  3. 3

    Cardiac & Pulmonary Assessment

    Echocardiogram, EKG, pulmonary function tests.

  4. 4

    Genomic Profiling

    NGS panel sent to lab; results take 1-3 weeks.

  5. 5

    Eligibility Confirmation

    Oncologist reviews all results and confirms treatment eligibility.

Frequently Asked Questions

About Pre-Treatment Testing

    How CancerFax Helps

    CancerFax is a specialist cancer access and patient-navigation platform. We help patients and families understand their options, organise medical records, coordinate hospital communication, and support cross-border treatment planning where appropriate.

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    Medical Record Review

    We help collect and organise reports, scans, pathology, biomarker results, and treatment history for structured case review.

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    Eligibility Coordination

    We communicate with hospitals or trial teams to assess whether a case may be suitable for further screening.

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    Hospital Communication

    We support appointment coordination, document submission, translation, and direct communication with international departments.

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    Travel & Admission Support

    For international patients, we help with practical coordination โ€” travel planning, hospital admission guidance, and local support.

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    Treatment & Trial Navigation

    If this option is not suitable, we help explore other relevant treatments, clinical trials, or advanced care pathways.

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    End-to-end Coordination

    From inquiry through to follow-up, our coordinators provide a single point of contact for the family.

    CancerFax does not guarantee treatment access, eligibility, or clinical outcome. Our role is to help patients access accurate information, structured review, and appropriate specialist pathways.

    Need Help Coordinating Pre-Treatment Testing?

    Upload your reports and our team will guide you through the required testing process for your specific treatment path.

    This content is for informational purposes only and does not constitute medical advice. Always consult a qualified oncologist before making treatment decisions.