Obesity and Early-Onset Colorectal Cancer Risk
According to a recent study published in JAMA Oncology, obesity is associated with an increased risk of early-onset colorectal cancer (CRC) in women.
A medical doctor from Boston Massachusetts General Hospital conducted a study to determine the occurrence of colorectal cancer in 85,256 women without cancer and inflammatory bowel disease based on data from 25-42 -year-old women .
The researchers discovered 114 cases of early-onset CRC (median age at diagnosis, 45 years) during the study period . For overweight women (body mass index [BMI] , 25-29.9 kg / m² ) and obese women (BMI, ≥30 kg / m²) with standard weight ( BMI is 18.5-22.9 kg / m² ) compared with women, CRC increased risk . This finding can be attributed to BMI at 18 years of age and weight gain after 18 years of age. For every 5 units of BMI increase , the RR (relative risk) of colorectal cancer increases by 1.2 . Comparative 18 years old BMI was 18.5-20.9 kg m² / female, BMI is 21 – 22.9 kg / m² women, early onset CRC of RRIs 1.32 , BMI is ≥23kg female RR was 1.63 . Similarly, compared with women who gained less than 5 kg or lost weight, women had an increase of 20-39.9 kg in early-onset CRC with an RR of 1.65 , women with an increase of ≥40 kg and an RR of 2.15.
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About Dr. Nishant Mittal
Dr. Nishant Mittal is a highly accomplished researcher with over 13 years of experience in the fields of cardiovascular biology and cancer research. Significant contributions to stem cell biology, developmental biology, and innovative research techniques mark his career. Research Highlights Dr. Mittal's research has focused on several key areas: 1) Cardio…
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