CancerFax
PRECISION ONCOLOGY

QUESTIONS TO ASK
ABOUT NGS TESTING

Prepared questions produce better information. The questions below direct the NGS results conversation toward what you need to know -- not just what you would receive in a standard briefing.

Reviewed by: CancerFax Medical Team, Oncology & Haematology SpecialistsLast reviewed: April 16, 20268 min read

Questions Organised by What You Are Trying to Find Out

  • Is the Testing Picture Complete?

    Was comprehensive genomic profiling done, or single/limited gene testing? Did the panel include TMB and MSI assessment? Was the tissue sample adequate? Should RNA sequencing be added to check for gene fusions the DNA panel might miss?

  • What Do the Specific Findings Mean?

    Which findings are Tier I or Tier II? Is there an FDA-approved therapy for this alteration in my cancer type? Is there a tumour-agnostic approval? Are any mutations acquired resistance mutations from prior treatment?

  • What Happens from Here?

    Should this case go to a molecular tumour board? What clinical trials are currently enrolling for my profile -- not the report list, but currently enrolling specifically? Are there basket trials open to my alteration regardless of cancer type?

  • Looking Forward

    Should comprehensive NGS be repeated at disease progression and with what timing? If liquid biopsy was used: what alterations might it have missed? Any finding suggesting a possible germline mutation: what is the process for germline testing?

Frequently Asked Questions

    How CancerFax Helps

    CancerFax is a specialist cancer access and patient-navigation platform. We help patients and families understand their options, organise medical records, coordinate hospital communication, and support cross-border treatment planning where appropriate.

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    Medical Record Review

    We help collect and organise reports, scans, pathology, biomarker results, and treatment history for structured case review.

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    Eligibility Coordination

    We communicate with hospitals or trial teams to assess whether a case may be suitable for further screening.

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    Hospital Communication

    We support appointment coordination, document submission, translation, and direct communication with international departments.

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    Travel & Admission Support

    For international patients, we help with practical coordination — travel planning, hospital admission guidance, and local support.

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    Treatment & Trial Navigation

    If this option is not suitable, we help explore other relevant treatments, clinical trials, or advanced care pathways.

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    End-to-end Coordination

    From inquiry through to follow-up, our coordinators provide a single point of contact for the family.

    CancerFax does not guarantee treatment access, eligibility, or clinical outcome. Our role is to help patients access accurate information, structured review, and appropriate specialist pathways.

    Want Expert Review of Your NGS Results Before Your Treatment Decision?

    CancerFax provides specialist review of NGS results and connects patients with molecular oncology expertise to ensure every actionable finding is properly assessed.

    This content is for informational purposes only and does not constitute medical advice. Always consult a qualified oncologist before making treatment decisions.