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Shing Chuan Hooi
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schoolMBBS, PhD (Harvard)

Dr.ย Shing Chuanย Hooi

MBBS, PhD

Professor & Cancer Biology Researcher

corporate_fareNUS Yong Loo Lin School of Medicine, Singapore

check_circleGI & Colorectal Cancer
check_circleLiver Cancer (HCC) Research
check_circleMedical Education
INSTITUTION
corporate_fareNUS Yong Loo Lin School of Medicine
DEPARTMENT
scienceDepartment of Physiology
SPECIALTY
medical_servicesCancer Biology & Translational Oncology Research
LOCATION
location_onSingapore
INTERNATIONAL PATIENTS
publicInternational Case Review Support
person

Shing Chuan Hooi

MBBS, PhD

Prof. Shing Chuan Hooi is a Singapore-based cancer biology researcher and medical educator at the Yong Loo Lin School of Medicine, National University of Singapore (NUS). His work centres on the molecular mechanisms that drive tumour growth, with a particular focus on gastrointestinal, colorectal and liver cancers.

He joined the NUS Department of Physiology in 1985 and has spent close to four decades in academic medicine and laboratory cancer research. His research interests include the regulation of C/EBPalpha in hepatocellular carcinoma, cancer cell survival under metabolic stress, and the mechanisms of cancer metastasis. Alongside his research, he is a recognised medical educator who served as Head of the Department of Physiology from 2000 to 2008 and has held senior education leadership roles within the school. His profile is most relevant for patients and referring doctors seeking a research-informed academic perspective on gastrointestinal and liver cancers within Singapore's academic cancer ecosystem.

workspace_premium40+Years Experience
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M
Visiting Days
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Academic & International Case Support

CancerFax can coordinate medical-record review and help international patients seek a research-informed academic opinion within Singapore's cancer care ecosystem, subject to availability and case acceptance.

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Why Consider Prof. Shing Chuan Hooi?

Prof. Hooi brings a research-driven academic perspective to complex gastrointestinal and liver cancers.

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Four Decades in Cancer Research
Has worked in academic medicine and laboratory cancer research at NUS since 1985, studying how genes drive tumour growth.
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GI & Liver Cancer Focus
Research centres on gastrointestinal, colorectal and hepatocellular carcinoma biology, including treatment-resistance mechanisms.
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Medical Education Leadership
A recognised medical educator and former Head of the Department of Physiology at NUS, with national teaching awards.
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Coordinated Academic Review
CancerFax can help international patients and doctors seek a research-informed academic opinion, with interpreter and logistics support where needed.
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Areas of Academic & Research Focus

Research-driven expertise in gastrointestinal and liver cancers

Prof. Hooi's expertise is grounded in laboratory and translational cancer research rather than routine clinical treatment. The areas below reflect his published research themes.

Research Focus Areas

Hepatocellular Carcinoma & Liver Cancer

Molecular biology of liver cancer and treatment-resistance mechanisms.

starsLiver Cancer Biology
  • arrow_rightRegulation and function of C/EBPalpha in hepatocellular carcinoma
  • arrow_rightLipid metabolism in liver cancer cells
starsTreatment-Resistance Research
  • arrow_rightACSL4 as a predictive biomarker of sorafenib sensitivity
  • arrow_rightSorafenib combined with glucose restriction in HCC models

Gastrointestinal & Colorectal Cancer

Tumour growth, survival and metastasis in gastrointestinal cancers.

starsColorectal Cancer Research
  • arrow_rightGene mechanisms that promote tumour growth
  • arrow_rightTumour-suppressor function and resistance to chemotherapy-induced apoptosis
starsCancer Metastasis
  • arrow_rightCytoskeletal dynamics and epithelial-mesenchymal transition
  • arrow_rightCancer cell survival under metabolic stress
Cancer Research Interests
check_circleHepatocellular Carcinoma (Liver Cancer)
check_circleColorectal Cancer
check_circleGastrointestinal Cancers
check_circleCancer Metastasis
check_circleTranslational Oncology
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Academic & Advisory Contributions

Research-informed review and academic support

Prof. Hooi is an academic researcher and educator. He does not provide routine clinical treatment through this profile. The support below reflects academic, advisory and second-opinion functions that CancerFax can help coordinate.

Expert Academic Opinion

Second Opinion

Research-informed academic perspective on complex gastrointestinal and liver cancer cases.

Case Review Support
arrow_rightReview of pathology and molecular findings from a research perspective
arrow_rightDiscussion of treatment-resistance biology in HCC and GI cancers
arrow_rightWritten academic perspective where appropriate

Translational Research Perspective

Complex Disease

Bridging laboratory cancer biology with clinical questions in difficult cases.

Research-Informed Guidance
arrow_rightInterpretation of biomarker and molecular pathology in the context of current research
arrow_rightPerspective on emerging treatment-resistance mechanisms

Multidisciplinary Academic Input

Multidisciplinary

Academic input within Singapore's research and teaching cancer ecosystem.

Academic Collaboration
arrow_rightEngagement with multidisciplinary academic discussion
arrow_rightResearch and education-led perspective on cancer management
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Research & Publications

Cancer biology research and peer-reviewed contributions

Prof. Hooi's research focuses on the molecular mechanisms of tumour growth, survival and metastasis, with particular emphasis on liver and gastrointestinal cancers.

Research Themes
arrow_rightRegulation and function of C/EBPalpha in hepatocellular carcinoma
arrow_rightACSL4 as a predictive biomarker of sorafenib sensitivity in liver cancer
arrow_rightSorafenib combined with glucose restriction in HCC models
arrow_rightCancer cell survival under metabolic stress and mechanisms of metastasis
Representative Publication
arrow_rightPro-survival function of DLEC1 protecting cancer cells against 5-FU-induced apoptosis via up-regulation of BCL-XL
Research Profile

A fuller list of Prof. Hooi's publications is available through his NUS and Google Scholar profiles, and can be shared on request via CancerFax.

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Education & Training

Prof. Hooi trained in medicine at the National University of Singapore and completed doctoral research at Harvard University.

Undergraduate
MBBS
National University of Singapore
1983
Bachelor of Medicine and Bachelor of Surgery.
Doctorate
PhD
Harvard University
1992
Doctoral research in the biomedical sciences.
work_history

Clinical Experience

Prof. Hooi has spent close to four decades at the National University of Singapore in cancer research and medical education, joining the Department of Physiology in 1985.

Professor, Department of Physiology
Yong Loo Lin School of Medicine, National University of Singapore
Cancer & Metastasis research; NUS Medicine education
check_circleCancer biology research โ€” gene mechanisms in tumour growth
check_circleHepatocellular carcinoma and liver cancer research
check_circleGastrointestinal and colorectal cancer research
check_circleUndergraduate and postgraduate medical education
check_circleFormer Head, Department of Physiology (2000 โ€“ 2008)
language

Languages & International

Prof. Hooi works in the following languages.

๐Ÿ‡ฌ๐Ÿ‡งEnglish
๐Ÿ‡จ๐Ÿ‡ณMandarin
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients.

CancerFax can coordinate professional medical interpreter support for international patients when required.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Shing Chuan Hooi

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Shing Chuan Hooi's team โ€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history โ€” prepared as a structured clinical summary for Dr. Shing Chuan Hooi's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Shing Chuan Hooi before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Shing Chuan Hooi's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Shing Chuan Hooi's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Shing Chuan Hooi's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Prof. Shing Chuan Hooi

Prof. Hooi is a senior cancer biology researcher and medical educator at the National University of Singapore. His expertise lies in the molecular biology of gastrointestinal and liver cancers and in medical education, rather than in providing routine day-to-day cancer treatment. CancerFax can help you understand how his research-informed perspective may support your case.

His research focuses on gastrointestinal cancers, colorectal cancer, and hepatocellular carcinoma (liver cancer), including how genes drive tumour growth, treatment resistance, and cancer metastasis.

CancerFax can coordinate medical-record review and help international patients seek a research-informed academic perspective and appropriate clinical referral within Singapore's academic cancer ecosystem, subject to availability and case acceptance.

Submit your medical reports through CancerFax. Our team will review the documents, prepare the case, and coordinate the next steps with the relevant academic or clinical team in Singapore, subject to availability.

A second-opinion request can be submitted through CancerFax with the patient's pathology reports, imaging, treatment history, and relevant test results. The final consultation format and availability depend on the institution and the doctor's academic commitments.

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Connect with Shing Chuan Hooi Today

Share your medical reports for a free preliminary review. Our patient coordinators will help you understand your options and arrange a direct consultation.

Free case review ยท No commitment ยท Response within 24 hours ยท Available in 12+ languages

Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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