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verifiedCancerFax Verified
schoolMD, MS, PhD – Ewha Womans University

Dr.Β Seock-AhΒ Im

MD, MS, PhD

Professor of Medical Oncology

corporate_fareSeoul National University Hospital, Seoul

check_circleBreast Cancer
check_circleHER2 & Targeted Therapy
check_circleImmunotherapy
check_circlePersonalised Oncology
INSTITUTION
corporate_fareSeoul National University Hospital
DEPARTMENT
scienceHemato-Oncology & Medical Oncology Center
SPECIALTY
medical_servicesBreast Cancer, Personalised Treatment, Clinical Trials
LOCATION
location_onSeoul, South Korea
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
person

Seock-Ah Im

MD, MS, PhD

Prof. Seock-Ah Im is one of South Korea's foremost academic medical oncologists, practising at Seoul National University Hospital where she is affiliated with the Hemato-Oncology Department, the Medical Oncology Center, and the Personalized Cancer Medicine Center. Her official clinical specialties include breast cancer, gastrointestinal stromal tumour, clinical trial care, and personalised treatment. She has been a Professor of Internal Medicine at Seoul National University College of Medicine since 2003.

With an oncology career spanning nearly three decades β€” from her clinical fellowship at Seoul National University Hospital in 1996 through to her current role as Director of the Cancer Research Institute at Seoul National University β€” Prof. Im has built an internationally recognised body of work in translational breast cancer research. Her academic profile lists over 600 peer-reviewed publications, an h-index of 96 on Scopus, and more than 64,000 citations, reflecting her stature as a global authority in HER2-positive, HER2-low, hormone receptor-positive, and triple-negative breast cancer. She has also held key leadership roles including Director of the Medical Oncology Center at Seoul National University Cancer Hospital, Chair of the Scientific Committee of the Korean Society of Medical Oncology, and Chair of the ESMO-PAGA Clinical Practice Guidelines Committee. Earlier in her career she completed a research fellowship in neuro-oncology at MD Anderson Cancer Center and served as a translational research scientist at AstraZeneca Oncology R&D in the United Kingdom.

workspace_premium29+Years Experience
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M
Visiting Days
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International Patients

CancerFax can coordinate medical-report review and consultation support for international patients seeking an opinion from Prof. Im at Seoul National University Hospital, subject to hospital availability and case acceptance.

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Why Consider Prof. Seock-Ah Im?

Prof. Seock-Ah Im combines decades of specialised breast cancer care with a world-class translational research programme, making her a strong choice for patients with advanced, metastatic, or treatment-resistant breast cancer who are seeking expert personalised treatment planning.

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Globally Recognised Research Profile
With over 600 published papers, an h-index of 96, and authorship on landmark trials including DESTINY-Breast03 and KEYNOTE-355, Prof. Im is among the most cited breast cancer oncologists in Asia.
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Pioneer in Personalised Breast Cancer Treatment
Her official SNUH profile lists personalised treatment as a core specialty, underpinned by active translational research in biomarker identification, HER2 biology, and therapeutic resistance mechanisms.
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Leadership in Clinical Trials
Clinical trial care is listed directly on her hospital profile. Her academic career includes contributions to major international breast cancer trials in HER2-positive, HER2-low, and triple-negative settings.
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International Research Collaboration
Prof. Im has trained at MD Anderson Cancer Center, worked at AstraZeneca Oncology R&D in the UK, and has contributed to global clinical trials, reflecting an international perspective in her clinical and research practice.
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Areas of Specialisation

Advanced breast cancer treatment, translational oncology, and personalised cancer medicine

Prof. Im's clinical and research work is centred on systemic treatment for breast cancer, with a particular focus on HER2-positive, HER2-low, hormone receptor-positive, and triple-negative subtypes. Her specialties also include gastrointestinal stromal tumour care and biomarker-driven clinical trial participation.

Clinical Specialties

Breast Cancer – HER2-Positive & HER2-Low

Advanced treatment planning for HER2-positive and HER2-low metastatic breast cancer, including antibody-drug conjugate and HER2-directed therapy.

starsHER2-Directed Therapy
  • arrow_rightAntibody-drug conjugate treatment including trastuzumab deruxtecan research
  • arrow_rightHER2-directed therapy assessment and treatment planning for eligible patients
  • arrow_rightBiomarker-guided treatment selection in HER2-positive and HER2-low settings
starsMetastatic Breast Cancer Management
  • arrow_rightSystemic therapy planning for advanced and metastatic disease
  • arrow_rightNeoadjuvant and adjuvant chemotherapy protocols
  • arrow_rightMultimodality and multidisciplinary care planning

Triple-Negative & Hormone Receptor-Positive Breast Cancer

Immunotherapy and endocrine-based treatment strategies for high-risk and advanced breast cancer subtypes.

starsImmunotherapy in Triple-Negative Breast Cancer
  • arrow_rightPembrolizumab-based immunotherapy for eligible patients
  • arrow_rightBiomarker assessment prior to immune checkpoint treatment
  • arrow_rightClinical trial participation including KEYNOTE programme contributions
starsEndocrine Therapy & CDK4/6 Inhibitors
  • arrow_rightEndocrine therapy for hormone receptor-positive breast cancer
  • arrow_rightCDK4/6 inhibitor-based regimens including palbociclib and ribociclib research
  • arrow_rightManagement of endocrine-resistant and refractory disease

Precision Oncology & Translational Research

Biomarker-driven treatment planning and translational science applied to breast cancer and selected other solid tumours.

starsBiomarker-Driven Treatment Planning
  • arrow_rightDNA damage repair and PARP-related therapeutic strategies
  • arrow_rightTumour microenvironment and immune biomarker analysis
  • arrow_rightTranslational laboratory work using patient-derived biospecimens
Cancer Types Treated
check_circleHER2-Positive Breast Cancer
check_circleHER2-Low & HER2-Ultralow Breast Cancer
check_circleTriple-Negative Breast Cancer
check_circleHormone Receptor-Positive Breast Cancer
check_circleMetastatic & Advanced Breast Cancer
check_circleGastrointestinal Stromal Tumour
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Procedures & Clinical Services

Systemic cancer treatment, personalised therapy, and clinical trial access

As a medical oncologist, Prof. Im's expertise is centred on systemic cancer therapy, biomarker-guided treatment planning, and clinical trial design and participation. The following represents her key clinical service areas based on verified sources.

Medical Oncology & Systemic Treatment

Medical Oncology

Comprehensive systemic treatment planning for breast cancer including chemotherapy, targeted therapy, immunotherapy, and endocrine-based approaches.

Treatment Approaches
arrow_rightChemotherapy protocols for neoadjuvant, adjuvant, and metastatic settings
arrow_rightPembrolizumab-based immunotherapy for eligible triple-negative breast cancer patients
arrow_rightEndocrine therapy including CDK4/6 inhibitor combinations

HER2-Directed & Targeted Therapy

Targeted Therapy

Molecularly guided treatment planning for HER2-positive and HER2-low breast cancer, including antibody-drug conjugate regimens and biomarker-driven selection.

HER2-Targeted Treatment
arrow_rightTrastuzumab deruxtecan and related HER2-directed antibody-drug conjugate therapy
arrow_rightHER2 biomarker testing and treatment stratification
arrow_rightManagement of HER2-positive disease progression

Personalised Cancer Medicine

Diagnosis

Biomarker-guided treatment planning through molecular profiling, translational research integration, and personalised oncology pathways.

Personalised Treatment Workup
arrow_rightPathology and biomarker assessment to guide systemic treatment selection
arrow_rightPARP inhibitor and DNA damage repair pathway evaluation
arrow_rightIntegration of translational research findings into individual care plans

Clinical Trial Access & Second Opinion

Second Opinion

Access to clinical trial programmes at Seoul National University and second-opinion consultation for complex breast cancer cases.

Trial & Consultation Services
arrow_rightFirst-in-human and biomarker-driven trial participation at SNUH Cancer Research Institute
arrow_rightSecond-opinion review of pathology, imaging, and treatment history
arrow_rightMultidisciplinary case discussion for advanced or refractory disease
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Research & Publications

Translational oncology, landmark clinical trials, and peer-reviewed contributions

Prof. Im has an extensive academic record in breast cancer and translational oncology. Seoul National University's research profile lists over 635 research outputs, an h-index of 96 on Scopus, and more than 64,000 citations. Her major research areas include HER2 biology, antibody-drug conjugates, triple-negative breast cancer immunotherapy, endocrine resistance, CDK4/6 inhibition, DNA damage repair, tumour microenvironment, and biomarker-driven clinical trials.

Selected Peer-Reviewed Publications
arrow_rightTrastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer (DESTINY-Breast03) – The Lancet, 2022
arrow_rightPembrolizumab plus chemotherapy in advanced triple-negative breast cancer (KEYNOTE-355) – The Lancet, 2020
arrow_rightTrastuzumab deruxtecan after endocrine therapy in metastatic breast cancer – New England Journal of Medicine, 2024
arrow_rightEvent-free survival with pembrolizumab in early triple-negative breast cancer (KEYNOTE-522)
arrow_rightRibociclib plus endocrine therapy in early breast cancer – major international trial contribution
Translational Research & Clinical Trial Leadership
arrow_rightDirector, Cancer Research Institute, Seoul National University – translational oncology team using patient-derived biospecimens for target identification and proof-of-concept clinical trials
arrow_rightResearch into therapeutic resistance, tumour microenvironment, tumour immunity, and biomolecular imaging
arrow_rightPrincipal contributor to first-in-human and biomarker-driven clinical trials within the Seoul National University cancer research ecosystem
arrow_rightBoard of Directors, Translation Research in Oncology (TRIO), from 2021
Research Profile

Prof. Im's full publication list is accessible via Seoul National University's research repository and Scopus. A more detailed list may be available on request through the hospital's international patient services.

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Education & Training

Prof. Im completed her undergraduate and postgraduate medical education at Ewha Womans University College of Medicine in Seoul, followed by specialised clinical training at Seoul National University Hospital and a research fellowship at MD Anderson Cancer Center in the United States.

Undergraduate
MD
Ewha Womans University College of Medicine, Seoul
1985 – 1991
Medical degree from one of South Korea's leading medical faculties.
Postgraduate
MS
Ewha Womans University College of Medicine, Seoul
1992 – 1995
Doctorate
PhD
Ewha Womans University College of Medicine, Seoul
1995 – 1999
Clinical Fellowship
Fellowship – Hematology-Medical Oncology
Seoul National University Hospital
1996 – 1997
Research Fellowship
Research Fellowship – Department of Neuro-Oncology
MD Anderson Cancer Center, Houston, Texas, USA
1997 – 1998
Industry Research Training
Translational Research Scientist
AstraZeneca Oncology R&D Center, Cheshire, UK
2008 – 2009
Specialised translational oncology research placement within AstraZeneca's oncology division.
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Clinical Experience

Prof. Im has been a Professor at Seoul National University College of Medicine since 2003 and has held successive directorial and committee leadership roles within South Korea's leading academic cancer institutions. Her career combines continuous clinical oncology practice with translational research leadership and major international trial participation.

Professor, Department of Internal Medicine
Seoul National University Hospital & Seoul National University College of Medicine
Cancer Research Institute, Seoul National University
check_circleDirector, Cancer Research Institute, Seoul National University (2019–present)
check_circleBoard of Directors, Translation Research in Oncology (2021–present)
check_circleFull Member, Korean Academy of Science and Technology (2024–present)
check_circleFormer Director, Medical Oncology Center, SNUH Cancer Hospital (2015–2022)
check_circleFormer Chair, Scientific Committee, Korean Society of Medical Oncology
check_circleFormer Chair, ESMO-PAGA Clinical Practice Guidelines Committee (2021–2023)
language

Languages & International

Verified language of consultation for Prof. Im based on her academic and institutional profile.

πŸ‡¬πŸ‡§English
πŸ‡°πŸ‡·Korean
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients consulting with Prof. Im.

CancerFax can coordinate medical interpreter support when required.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Seock-Ah Im

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Seock-Ah Im's team β€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history β€” prepared as a structured clinical summary for Dr. Seock-Ah Im's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Seock-Ah Im before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Seock-Ah Im's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Seock-Ah Im's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Seock-Ah Im's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Prof. Seock-Ah Im

Prof. Seock-Ah Im's official Seoul National University Hospital profile lists breast cancer and gastrointestinal stromal tumour as her primary specialties. Her clinical and research focus is especially strong in HER2-positive, HER2-low, triple-negative, and hormone receptor-positive breast cancer, including advanced and metastatic disease.

Seoul National University Hospital has a global-facing website with international patient access. CancerFax can coordinate medical-report review and consultation support for international patients seeking an opinion from Prof. Im, subject to hospital availability and case acceptance. Please submit your reports through CancerFax to begin the process.

Submit your medical reports through CancerFax. The CancerFax team will review the documents, prepare the case for submission, and coordinate the next steps with the hospital, subject to availability. Reports typically needed include pathology, imaging, biopsy results, and current treatment history.

A second-opinion request can be submitted through CancerFax with the patient's pathology reports, imaging, treatment history, and relevant biomarker or genetic test results. The final consultation format and availability depend on Seoul National University Hospital's international patient services.

Prof. Im's research and clinical work covers immunotherapy including pembrolizumab-based treatment in triple-negative breast cancer, HER2-directed antibody-drug conjugate therapy including trastuzumab deruxtecan, CDK4/6 inhibitor-based endocrine therapy, PARP inhibitor strategies for DNA damage repair-related breast cancer, and biomarker-driven personalised treatment planning. She has been a contributor to major international trials across each of these areas.

Yes. Clinical trial care is listed on her official Seoul National University Hospital profile, and her academic record includes contributions to major international breast cancer trials such as DESTINY-Breast03 and KEYNOTE-355. As Director of the Cancer Research Institute at Seoul National University, she oversees translational oncology work that includes proof-of-concept and first-in-human clinical trials.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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