CancerFax
Patrick Wen
verifiedCancerFax Verified
schoolBoard Certified Neuro-Oncology

Dr.ย Patrickย Wen

MBBS, Board Certified Neurology & Neuro-Oncology

Director, Center for Neuro-Oncology

corporate_fareDana-Farber Cancer Institute, Boston

check_circleGlioma & Glioblastoma
check_circleBrain Tumour Trials
check_circleAnti-Angiogenic Therapy
check_circleRANO 2.0 Contributor
INSTITUTION
corporate_fareDana-Farber Cancer Institute & Brigham and Women's Hospital
DEPARTMENT
scienceCenter for Neuro-Oncology
SPECIALTY
medical_servicesBrain Tumours, Glioma, Glioblastoma, Neuro-Oncology
LOCATION
location_onBoston, United States
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
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Patrick Wen

MBBS, Board Certified Neurology & Neuro-Oncology

Dr. Patrick Y. Wen is Director of the Center for Neuro-Oncology at Dana-Farber Cancer Institute and Professor of Neurology at Harvard Medical School, where he has led brain tumour care and research for several decades. He also serves as Director of the Neuro-Oncology Division at Brigham and Women's Hospital and is a member of the Neuro-Oncology Program at Dana-Farber/Harvard Cancer Center.

Dr. Wen completed his medical training at the University of London and undertook residency through the Harvard / MGB Combined Training Programme, earning board certifications in both Neurology and Neuro-Oncology. His clinical practice focuses on adults with brain and spinal cord tumours, including glioma, glioblastoma, high-grade and low-grade gliomas, and leptomeningeal metastases. His research programme has explored gene therapy, inhibitors of angiogenesis, hormonal therapy, radionuclide-based strategies, and the neurological complications of cancer treatment. He is closely associated with the Response Assessment in Neuro-Oncology (RANO) framework and led the international effort to develop RANO 2.0, a unified set of criteria for assessing response and progression in adult gliomas across clinical trials.

workspace_premium40+Years Experience
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M
Visiting Days
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International Patient Coordination

CancerFax can coordinate medical-record review and consultation support for international patients seeking an opinion from Dr. Wen at Dana-Farber Cancer Institute, subject to hospital availability and case acceptance.

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Why Consider Dr. Patrick Wen?

Dr. Wen brings more than four decades of neuro-oncology expertise, leading one of the world's foremost brain tumour programmes at a Harvard-affiliated cancer centre.

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Director at a World-Leading Cancer Centre
Dr. Wen leads the Center for Neuro-Oncology at Dana-Farber Cancer Institute and the Neuro-Oncology Division at Brigham and Women's Hospital โ€” institutions consistently ranked among the top cancer centres in the United States.
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Architect of Glioma Response Standards
Dr. Wen proposed and led the development of RANO 2.0, the updated international criteria for assessing treatment response and tumour progression in adult gliomas, now used across global clinical trials.
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Broad Research in Advanced Brain Tumour Therapies
His research spans anti-angiogenic therapy, gene therapy, radionuclide-based treatment, and targeted molecular approaches for brain tumours and leptomeningeal metastases.
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Multidisciplinary Team-Based Care
Patients at the Center for Neuro-Oncology receive care from a team that includes neuro-oncologists, neurosurgeons, radiation oncologists, neuropathologists, specialist nurses, and supportive care professionals.
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Areas of Specialisation

Adult brain and central nervous system tumour care, with a research focus on glioma and novel brain tumour therapies

Dr. Wen's clinical and research specialisation centres on adult neuro-oncology, encompassing primary brain tumours and neurological complications in cancer patients.

Clinical Specialities

Glioma & Glioblastoma

Diagnosis, treatment planning, and clinical trial evaluation for adults with high-grade and low-grade gliomas.

starsHigh-Grade Glioma & Glioblastoma
  • arrow_rightTreatment planning for newly diagnosed and recurrent glioblastoma
  • arrow_rightAssessment of treatment response using RANO and RANO 2.0 criteria
  • arrow_rightClinical trial options for eligible patients with recurrent high-grade glioma
starsLow-Grade Glioma
  • arrow_rightEvaluation of low-grade glioma behaviour and progression risk
  • arrow_rightIndividualised treatment planning including observation, radiotherapy, and systemic therapy

Brain Tumour Clinical Trials & Novel Therapies

Active participation in clinical trial development for brain tumours and research into new treatment strategies.

starsClinical Trial Evaluation
  • arrow_rightEvaluation of eligibility for brain tumour clinical trials at Dana-Farber
  • arrow_rightPI3K/mTOR inhibitor trials for recurrent high-grade glioma
starsExperimental Therapeutic Approaches
  • arrow_rightAnti-angiogenic therapy research for brain tumours
  • arrow_rightGene therapy and radionuclide-based therapeutic research
  • arrow_rightHormonal and molecularly targeted approaches under investigation

Leptomeningeal Metastases & Neurological Complications

Specialist care for brain and spinal cord involvement from systemic cancers, and neurological complications arising during cancer treatment.

starsLeptomeningeal Metastases
  • arrow_rightDiagnosis and treatment planning for leptomeningeal spread of cancer
  • arrow_rightEvaluation of systemic and intrathecal treatment options
starsNeurological Complications of Cancer
  • arrow_rightAssessment and management of nervous system complications arising from cancer or its treatment
Cancer Types & Clinical Focus Areas
check_circleGlioblastoma (GBM)
check_circleHigh-Grade Glioma
check_circleLow-Grade Glioma
check_circleBrain & Spinal Cord Tumours
check_circleLeptomeningeal Metastases
check_circleNeurological Complications of Cancer
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Procedures & Clinical Services

Neuro-oncology evaluation, brain tumour treatment planning, and clinical trial coordination at Dana-Farber Cancer Institute

Dr. Wen provides specialist neuro-oncology evaluation and treatment planning within a multidisciplinary team setting, with access to active clinical trials for eligible patients.

Neuro-Oncology Evaluation & Treatment Planning

Medical Oncology

Comprehensive assessment and treatment planning for adults with brain and CNS tumours.

Initial & Follow-Up Assessment
arrow_rightDiagnostic review of MRI, pathology, and molecular profiling
arrow_rightTreatment response assessment using RANO and RANO 2.0 criteria
arrow_rightMultidisciplinary care coordination with neurosurgery, radiation oncology, and pathology

Systemic Brain Tumour Treatment

Targeted Therapy

Systemic therapy options for primary brain tumours, including targeted and experimental approaches.

Treatment Options
arrow_rightTemozolomide-based chemotherapy regimens for glioma
arrow_rightAnti-angiogenic therapy (e.g. bevacizumab) for recurrent glioblastoma
arrow_rightTargeted molecular therapy based on tumour profiling where applicable

Clinical Trial Participation

Complex Disease

Access to brain tumour clinical trials at Dana-Farber Cancer Institute for eligible patients.

Trial Access
arrow_rightEligibility evaluation for active neuro-oncology clinical trials
arrow_rightPI3K/mTOR pathway inhibitor trials for recurrent high-grade glioma
arrow_rightNovel immunotherapy and gene therapy protocols under investigation

Second Opinion โ€“ Brain Tumour

Second Opinion

Expert second-opinion review of brain tumour diagnosis, pathology, and treatment plan.

Second Opinion Services
arrow_rightReview of pathology reports and molecular tumour markers
arrow_rightIndependent assessment of imaging findings and treatment response
arrow_rightRecommendation on alternative or additional treatment strategies where supported

Multidisciplinary Brain Tumour Care

Multidisciplinary

Coordinated care within the Dana-Farber Center for Neuro-Oncology's specialist team.

Team-Based Care
arrow_rightNeurosurgery, radiation oncology, neuropathology, and neuro-oncology collaboration
arrow_rightSpecialist nursing and supportive care integrated into the treatment programme
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Research & Publications

Contributions to glioma treatment science, clinical trial development, and international response assessment standards

Dr. Wen has contributed extensively to brain tumour research, with particular impact in glioma response assessment, targeted therapeutics, and clinical trial methodology.

Selected Peer-Reviewed Research
arrow_rightRANO 2.0: Updated response assessment criteria for high- and low-grade gliomas in adults โ€“ proposed by Dr. Wen and an international team of neuro-oncologists and neuroradiologists, Dana-Farber Cancer Institute, 2023
arrow_rightFirst-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Recurrent High-Grade Glioma โ€“ PubMed PMID 31937616
arrow_rightSNO and EANO consensus review on adult glioblastoma management and future directions โ€“ co-authored with Dana-Farber Cancer Institute and Harvard Medical School, 2025
Research Focus Areas
arrow_rightGlioma and glioblastoma clinical trial development and response evaluation
arrow_rightLeptomeningeal metastases treatment strategies
arrow_rightAnti-angiogenic therapy for brain tumours
arrow_rightGene therapy approaches in primary brain tumours
arrow_rightRadionuclide-based brain tumour therapeutics
arrow_rightNeurological complications of systemic cancer treatment
Extensive Publication Record

Dr. Wen has authored and co-authored a substantial body of peer-reviewed neuro-oncology research. A full publication list is available via PubMed and Harvard Medical School faculty pages.

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Education & Training

Dr. Wen trained in medicine at the University of London and undertook postgraduate neurology residencies in the United Kingdom before completing further residency training through the Harvard / MGB Combined Neurology Programme. He holds board certifications in Neurology and Neuro-Oncology.

Undergraduate
MBBS
University of London
1975 โ€“ 1981
Postgraduate Training
Internship
St. Bartholomew's Hospital, London
1981 โ€“ 1982
Postgraduate Training
Neurology Residency
Whittington / Royal Northern Hospital & National Hospital for Nervous Diseases, London
1982 โ€“ 1984
Postgraduate Training
Neurology Residency
Harvard / MGB Combined Neurology Training Programme
1985 โ€“ 1988
Board Certification
Board Certification โ€“ Neurology
American Board of Psychiatry and Neurology
1989
Board Certification
Board Certification โ€“ Neuro-Oncology
United Council for Neurologic Subspecialties
2008
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Clinical Experience

Dr. Wen has spent his career at Dana-Farber Cancer Institute and Harvard Medical School, building and directing one of the United States' foremost neuro-oncology programmes.

Director, Center for Neuro-Oncology
Dana-Farber Cancer Institute
Professor of Neurology, Harvard Medical School; Director, Neuro-Oncology Division, Brigham and Women's Hospital
check_circleDirector, Center for Neuro-Oncology, Dana-Farber Cancer Institute
check_circleProfessor of Neurology, Harvard Medical School
check_circleDirector, Neuro-Oncology Division, Brigham and Women's Hospital
check_circleMember, Neuro-Oncology Program, Dana-Farber/Harvard Cancer Center
check_circleMultidisciplinary neuro-oncology care and clinical trial leadership
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Languages & International

Dr. Wen consults in English. Additional languages were not confirmed from public sources.

๐Ÿ‡ฌ๐Ÿ‡งEnglish
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients seeking care at Dana-Farber Cancer Institute.

CancerFax can coordinate professional medical interpreter support for international patients when required.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Patrick Wen

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Patrick Wen's team โ€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history โ€” prepared as a structured clinical summary for Dr. Patrick Wen's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Patrick Wen before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Patrick Wen's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Patrick Wen's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Patrick Wen's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Dr. Patrick Wen

Dr. Patrick Wen specialises in adult neuro-oncology, with a particular focus on glioblastoma, high-grade and low-grade gliomas, brain and spinal cord tumours, and leptomeningeal metastases. He also manages neurological complications that arise during cancer treatment.

Dr. Wen is based at Dana-Farber Cancer Institute and Brigham and Women's Hospital in Boston, Massachusetts. He directs the Center for Neuro-Oncology at Dana-Farber and the Neuro-Oncology Division at Brigham and Women's Hospital, and holds a professorship at Harvard Medical School.

A second-opinion request for Dr. Wen can be submitted through CancerFax with the patient's MRI reports, pathology results, molecular tumour profiling, and current treatment history. The CancerFax team will prepare the case and coordinate the next steps with Dana-Farber Cancer Institute, subject to availability and case acceptance.

Submit your medical reports โ€” including MRI scans, pathology, and treatment records โ€” through the CancerFax upload portal. The CancerFax team will review the documents, prepare the case for submission, and coordinate with Dana-Farber Cancer Institute on the next steps, subject to the institution's availability.

Dana-Farber Cancer Institute treats patients from many countries. CancerFax can support international patients by coordinating report review and consultation pathways with the institution. Patients should contact CancerFax or Dana-Farber directly to confirm current international patient intake procedures.

RANO 2.0 is an updated international framework for assessing how well treatments are working in patients with adult gliomas โ€” both high-grade and low-grade. It standardises how oncologists and researchers measure tumour response and progression in clinical trials, which helps ensure that promising new treatments are evaluated accurately. Dr. Wen proposed and led the development of RANO 2.0 with an international team of neuro-oncologists and neuroradiologists.

Dana-Farber Cancer Institute runs active clinical trials in neuro-oncology, and Dr. Wen has been involved in trial development for brain tumours, including studies on targeted PI3K/mTOR inhibitors for recurrent high-grade glioma. CancerFax can help coordinate the inquiry process for international patients who wish to explore clinical trial eligibility, subject to Dana-Farber's intake criteria.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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