CancerFax
Matthew Ng
verifiedCancerFax Verified
schoolPhD, Institute of Cancer Research London

Dr.ย Matthewย Ng

MBBS (London), MRCP (UK), PhD (UK)

Senior Consultant & Head of Department of GI Oncology

corporate_fareNational Cancer Centre Singapore

check_circleGI Oncology
check_circleEarly-Phase Trials
check_circleColorectal & Gastric Cancer
check_circlePeritoneal Malignancies
INSTITUTION
corporate_fareNational Cancer Centre Singapore
DEPARTMENT
scienceDepartment of GI Oncology
SPECIALTY
medical_servicesGastrointestinal Oncology
LOCATION
location_onSingapore
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
person

Matthew Ng

MBBS (London), MRCP (UK), PhD (UK)

Dr. Matthew Ng Chau Hsien is a Senior Consultant and Head of the Department of GI Oncology at the National Cancer Centre Singapore (NCCS), with a specialised clinical and research focus in gastrointestinal cancers. He holds academic appointments as Clinical Associate Professor at Duke-NUS Medical School and within the SingHealth Duke-NUS Oncology Academic Clinical Programme.

Dr. Ng's clinical practice spans the full breadth of gastrointestinal oncology, including colorectal cancer, gastric and oesophageal cancer, pancreatic cancer, liver cancer, bile duct and biliary tract cancers, and peritoneal-based malignancies. He leads upper GI cancer services at SingHealth and serves as Director of the Investigational Medicine Unit, overseeing early-phase clinical trials at NCCS. His research interests centre on novel therapeutics for GI cancers, biomarker-driven treatment development, and peritoneal-directed therapy strategies. Dr. Ng co-chairs the GI cancers service line delivery within the SingHealth Academic Medical Health Cluster and chairs the Named Patient Programme at NCCS. He is a member of the Singapore Gastric Cancer Consortium, the Singapore Peritoneal Oncology Study Group, and the Singapore Translational Cancer Consortium GI and Early Phase Trials track.

calendar_month
M
Visiting Days
public
International Patient Access

CancerFax can coordinate medical-record review, case preparation, and consultation support for international patients seeking an opinion from Dr. Matthew Ng at the National Cancer Centre Singapore.

stars

Why Consider Dr. Matthew Ng?

Dr. Matthew Ng combines leadership of Singapore's foremost GI oncology department with an active research programme in early-phase trials, biomarker development, and novel therapeutic strategies โ€” making him a highly relevant specialist for patients with complex or advanced gastrointestinal cancers.

local_hospital
Head of GI Oncology at NCCS
As Head of the Department of GI Oncology at the National Cancer Centre Singapore, Dr. Ng leads multidisciplinary care for the full range of GI cancers at Singapore's national cancer centre.
science
Early-Phase Clinical Trial Leadership
Dr. Ng directs the Investigational Medicine Unit at SingHealth, overseeing early-phase clinical trials for GI cancers and providing eligible patients with access to novel investigational therapies.
biotech
Biomarker-Driven Treatment Approach
His research programme focuses on biomarker development for diagnostics and therapeutics in GI cancers, enabling more precise treatment planning for patients with gastric, oesophageal, and colorectal cancers.
emoji_events
Academic Recognition and Publications
Dr. Ng has published in leading journals including The Lancet Oncology, Lancet Gastroenterology & Hepatology, Annals of Oncology, and Clinical Cancer Research, reflecting a sustained contribution to GI oncology evidence.
verified_user

Areas of Specialisation

Focused expertise across the full spectrum of gastrointestinal cancers, peritoneal disease, and early-phase oncology drug development

Dr. Matthew Ng's specialisation covers lower and upper gastrointestinal cancers, hepatobiliary malignancies, peritoneal-based disease, and early-phase clinical research. His clinical and academic work spans systemic therapy, biomarker-driven treatment, and novel GI cancer strategies.

Specialisation Areas

Lower GI & Colorectal Oncology

Systemic therapy and multidisciplinary management for colorectal cancer.

starsColorectal Cancer
  • arrow_rightSystemic therapy planning for localised and metastatic colorectal cancer
  • arrow_rightBiomarker-guided treatment selection including MSI, KRAS, BRAF, and HER2 status
  • arrow_rightPeritoneal metastasis management in colorectal cancer

Upper GI Cancers

Leadership of upper GI cancer services at SingHealth, with a focus on gastric, oesophageal, and gastroesophageal junction cancers.

starsGastric and Gastroesophageal Cancer
  • arrow_rightSystemic and targeted therapy for gastric and gastroesophageal junction adenocarcinoma
  • arrow_rightHER2-positive gastric cancer treatment including margetuximab and pembrolizumab combinations
  • arrow_rightPan-Asian clinical practice guideline contributor for metastatic gastric cancer
starsOesophageal Cancer
  • arrow_rightSystemic treatment for oesophageal squamous cell carcinoma and adenocarcinoma
  • arrow_rightPan-Asian adapted ESMO guideline contributor for metastatic oesophageal cancer

Hepatopancreaticobiliary Cancers

Medical oncology for cancers of the liver, pancreas, and biliary tract.

starsPancreatic Cancer
  • arrow_rightSystemic therapy for advanced pancreatic adenocarcinoma
  • arrow_rightPhase I trial participation in novel pancreatic cancer drug development (OXIRI regimen)
starsLiver, Bile Duct, and Biliary Tract Cancers
  • arrow_rightHepatocellular carcinoma management including radioembolisation with Y90 and immunotherapy combinations
  • arrow_rightBiliary tract and bile duct cancer systemic therapy

Peritoneal-Based Malignancies

Specialist management of peritoneal disease arising from GI primary cancers.

starsPeritoneal Oncology
  • arrow_rightPeritoneal metastases from colorectal, gastric, and other GI primaries
  • arrow_rightPeritoneal-directed therapy development and research through the Singapore Peritoneal Oncology Study Group
Clinical Focus Areas
check_circleColorectal Cancer
check_circleGastric & Oesophageal Cancer
check_circlePancreatic Cancer
check_circleLiver, Bile Duct & Biliary Tract Cancers
check_circlePeritoneal-Based Malignancies
check_circleEarly-Phase Clinical Trials
medical_services

Procedures & Clinical Services

Treatment approaches and investigational programmes offered through the National Cancer Centre Singapore

Dr. Matthew Ng provides medical oncology services for the full range of gastrointestinal cancers, with particular expertise in systemic therapy, targeted therapy, and early-phase clinical trial administration through the Investigational Medicine Unit at SingHealth.

Systemic Therapy for GI Cancers

Medical Oncology

Comprehensive systemic treatment planning and administration for all major gastrointestinal malignancies.

Chemotherapy and Combination Regimens
arrow_rightStandard-of-care chemotherapy regimens for colorectal, gastric, and pancreatic cancers
arrow_rightCombination protocols including mFOLFOX6, OXIRI, XELOX, and ECF/FLOT variants
arrow_rightPerioperative and palliative systemic therapy planning

Targeted Therapy and Immunotherapy

Targeted Therapy

Molecularly targeted and immunotherapy-based treatment for eligible GI cancer patients.

Targeted and Immunotherapy Approaches
arrow_rightHER2-targeted therapy for gastric and gastroesophageal junction cancers
arrow_rightCheckpoint inhibitor therapy for eligible colorectal, gastric, and oesophageal cancers
arrow_rightAKT pathway inhibitors and other biomarker-selected therapies in trial and clinical settings
arrow_rightRadioembolisation with Y90 plus immunotherapy for hepatocellular carcinoma

Early-Phase Clinical Trials

Complex Disease

Access to novel investigational agents and early-phase studies through the SingHealth Investigational Medicine Unit.

Investigational Drug Programmes
arrow_rightPhase I and Phase II trials for advanced GI cancers
arrow_rightBiomarker-integrated early-phase study designs
arrow_rightTrial eligibility assessment for patients with advanced or refractory GI cancers

Multidisciplinary Tumour Board Review

Multidisciplinary

Complex GI cancer cases reviewed within a multidisciplinary team framework at NCCS and SingHealth.

Multidisciplinary Case Review
arrow_rightGI cancer service line coordination across SingHealth Academic Medical Health Cluster
arrow_rightComplex peritoneal malignancy case discussion and peritoneal-directed therapy planning
arrow_rightSecond-opinion review for advanced or rare GI cancers

Second Opinion for GI Cancers

Second Opinion

Expert second-opinion review for patients with gastrointestinal cancers seeking assessment from a Singapore-based GI oncology specialist.

Second Opinion Services
arrow_rightPathology and imaging review for GI malignancies
arrow_rightTreatment plan assessment for gastric, colorectal, pancreatic, and hepatobiliary cancers
arrow_rightClinical trial suitability review for patients with advanced GI cancers
menu_book

Research & Publications

Clinical research in gastrointestinal oncology, early-phase trials, and biomarker-driven treatment development

Dr. Matthew Ng has an active publication record in gastrointestinal oncology, with contributions to landmark studies in gastric, oesophageal, colorectal, and hepatocellular carcinoma. His research focuses on early-phase clinical trials incorporating biomarker analyses, biomarker development for GI cancer diagnostics and therapeutics, and novel therapeutic strategies for upper GI and peritoneal disease.

Selected Peer-Reviewed Publications
arrow_rightMargetuximab plus pembrolizumab in HER2-positive gastro-oesophageal adenocarcinoma โ€” The Lancet Oncology
arrow_rightA phase II randomised study of mFOLFOX6 with or without ipatasertib in gastric or gastroesophageal junction cancer โ€” European Journal of Cancer
arrow_rightPan-Asian adapted ESMO Clinical Practice Guidelines for metastatic oesophageal cancer and metastatic gastric cancer โ€” Annals of Oncology
arrow_rightReal-time tumour gene expression profiling to direct gastric cancer chemotherapy โ€” Clinical Cancer Research
arrow_rightRadioembolisation with Y90-resin microspheres followed by nivolumab for advanced hepatocellular carcinoma โ€” Lancet Gastroenterology & Hepatology
Clinical Trial Participation
arrow_rightPhase I trial of OXIRI for advanced and metastatic pancreatic adenocarcinoma
arrow_rightMargetuximab plus pembrolizumab for HER2-positive gastric and gastroesophageal junction cancer
arrow_rightASLAN001 with oxaliplatin and capecitabine in advanced GI cancers
arrow_rightETC-1922159 in advanced solid tumours
Early-Phase Trial Access

Dr. Ng directs the Investigational Medicine Unit at SingHealth. Patients with advanced GI cancers may be eligible for early-phase investigational studies. CancerFax can assist with case preparation for assessment.

school

Education & Training

Dr. Matthew Ng completed his undergraduate medical training in London, obtained Membership of the Royal College of Physicians in the United Kingdom, and earned a PhD from the Institute of Cancer Research, University of London.

Undergraduate
MBBS (London)
St. Bartholomew's and the Royal London Hospital School of Medicine and Dentistry, University of London
Awarded the Brackenbury and Bourne Scholarship in Clinical Medicine (2000), Heath Skynner Prize in Paediatrics (2000), and Draper's Prize for academic achievement. Proxime Accessit to the University of London Gold Medal.
Postgraduate
MRCP (UK)
Royal College of Physicians, United Kingdom
Doctoral
PhD
Institute of Cancer Research / University of London, United Kingdom
Doctoral research focused on gastrointestinal cancer biology and therapeutic development.
work_history

Clinical Experience

Dr. Matthew Ng has built his entire specialist career in GI oncology at the National Cancer Centre Singapore and the SingHealth Academic Medical Health Cluster, rising to lead Singapore's GI oncology department and its early-phase clinical trial unit.

Senior Consultant and Head of Department of GI Oncology
National Cancer Centre Singapore
SingHealth Duke-NUS Oncology Academic Clinical Programme
check_circleHead of GI Oncology, National Cancer Centre Singapore
check_circleClinical Associate Professor, Duke-NUS Medical School
check_circleDirector, Investigational Medicine Unit, SingHealth
check_circleCo-Chair, GI Cancer Service Line Delivery, SingHealth AMHC
check_circleChair, Named Patient Programme, NCCS
check_circleMember, Singapore Gastric Cancer Consortium and Singapore Peritoneal Oncology Study Group
language

Languages & International

Dr. Matthew Ng consults in the following language.

๐Ÿ‡ฌ๐Ÿ‡งEnglish
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients consulting at the National Cancer Centre Singapore.

CancerFax can coordinate professional medical interpreter support for international patients requiring consultation in other languages.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Matthew Ng

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Matthew Ng's team โ€” with full coordination from initial inquiry to consultation.

description

Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history โ€” prepared as a structured clinical summary for Dr. Matthew Ng's team.

medical_services

Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Matthew Ng before you travel, so you arrive with a clear pathway.

send

Case Submission

We coordinate direct case submission to Dr. Matthew Ng's department, including all documentation required for clinical review and appointment scheduling.

calendar_month

Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Matthew Ng's team, confirming availability and aligning timelines with your travel plans.

flight_takeoff

Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

support_agent

Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Matthew Ng's team and your home oncologist for seamless post-treatment follow-up.

quiz

Frequently Asked Questions About Dr. Matthew Ng

Dr. Matthew Ng is a gastrointestinal oncology specialist. He treats colorectal cancer, gastric cancer, oesophageal cancer, pancreatic cancer, liver cancer, bile duct cancer, biliary tract cancer, and peritoneal-based malignancies. He leads upper GI cancer services at SingHealth and is Head of the Department of GI Oncology at the National Cancer Centre Singapore.

Dr. Matthew Ng's verified current affiliation is the National Cancer Centre Singapore (NCCS), where he is listed as Senior Consultant and Head of the Department of GI Oncology. He also holds an academic appointment as Clinical Associate Professor at Duke-NUS Medical School within the SingHealth Duke-NUS Oncology Academic Clinical Programme.

The National Cancer Centre Singapore provides an appointment pathway for patients including international visitors. CancerFax can coordinate medical-record preparation, case review, and consultation support for international patients seeking an opinion from Dr. Matthew Ng, subject to hospital availability and case acceptance.

You can submit your medical records and reports through CancerFax. The CancerFax team will review the documents, prepare the case for submission, and coordinate the next steps with the hospital, subject to availability. A second-opinion request should include pathology reports, imaging, relevant tumour marker results, and prior treatment history.

Yes. Dr. Ng serves as Director of the Investigational Medicine Unit at SingHealth, overseeing early-phase clinical trials for gastrointestinal cancers. He has participated in trials evaluating novel agents for gastric, oesophageal, pancreatic, and hepatocellular carcinoma. Patients with advanced or refractory GI cancers may be assessed for trial eligibility. CancerFax can assist with case preparation for evaluation.

Dr. Matthew Ng holds MBBS (London) from St. Bartholomew's and the Royal London Hospital School of Medicine and Dentistry, Membership of the Royal College of Physicians (MRCP, UK), and a PhD from the Institute of Cancer Research, University of London. He received multiple academic prizes during his undergraduate training including the Brackenbury and Bourne Scholarship and the Draper's Prize.

sendGet Expert Oncology Guidance

Connect with Matthew Ng Today

Share your medical reports for a free preliminary review. Our patient coordinators will help you understand your options and arrange a direct consultation.

Free case review ยท No commitment ยท Response within 24 hours ยท Available in 12+ languages

Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

upload_fileUpload ReportschatWhatsApp