CancerFax
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verifiedCancerFax Verified
schoolPh.D. Molecular Oncology ยท Seoul National University

Dr.ย Keun-Wookย Lee

M.D., M.S. (Internal Medicine), Ph.D. (Molecular Oncology)

Professor, Hematology & Medical Oncology | Chief Director, Comprehensive Cancer Center

corporate_fareSeoul National University Bundang Hospital, South Korea

check_circleGastric & GI Cancer
check_circleClinical Trials
check_circleSystemic Oncology
check_circleHead & Neck Cancer
INSTITUTION
corporate_fareSeoul National University Bundang Hospital
DEPARTMENT
scienceHematology & Medical Oncology
SPECIALTY
medical_servicesGastric, GI & Head and Neck Cancer
LOCATION
location_onSeongnam, South Korea
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
person

Keun-Wook Lee

M.D., M.S. (Internal Medicine), Ph.D. (Molecular Oncology)

Prof. Keun-Wook Lee is a Professor of Internal Medicine and Chief Director of the Comprehensive Cancer Center at Seoul National University Bundang Hospital, one of South Korea's leading academic medical centres. He specialises in gastrointestinal cancers โ€” including gastric, colorectal, and gastroesophageal junction cancer โ€” as well as head and neck cancer, with a particular focus on chemotherapy and early-phase clinical trials.

Prof. Lee completed his M.D. at Seoul National University College of Medicine in 1998, followed by postgraduate training leading to an M.S. in Internal Medicine and a Ph.D. in Molecular Oncology from Seoul National University Graduate School. He has been based at Seoul National University Bundang Hospital since 2005, rising to Full Professor in 2018. He broadened his research expertise with a visiting professorship in the Department of Systems Biology at MD Anderson Cancer Center from 2012 to 2013. As of 2025, his official hospital profile credits him with more than 300 peer-reviewed scientific articles, and Seoul National University's research portal records 328 research outputs, 18,468 citations, and an h-index of 60. He currently also serves as Chief Director of the Clinical Trial Center at SNUBH, a role he has held since 2020.

workspace_premium20+Years Experience
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Visiting Days
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International Patient Coordination

CancerFax can coordinate medical-report review and consultation support for international patients seeking an expert opinion from Prof. Lee at Seoul National University Bundang Hospital.

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Why Consider Prof. Keun-Wook Lee?

Prof. Lee combines two decades of academic oncology with institutional leadership in clinical trials and cancer care, making him a highly relevant choice for patients with advanced gastric, gastrointestinal, and head and neck cancers.

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300+ Peer-Reviewed Publications
Prof. Lee's official SNUBH profile confirms more than 300 scientific articles, with an h-index of 60 and over 18,000 citations recorded in Seoul National University's research portal.
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Leading Clinical Trials Programme
As Chief Director of the Clinical Trial Center at SNUBH since 2020, Prof. Lee has led and participated in early-phase and phase III trials in gastric and gastroesophageal cancers, including nivolumab, tislelizumab, bemarituzumab, and zanidatamab studies.
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Comprehensive Cancer Centre Leadership
Since 2024, Prof. Lee has served as Chief Director of the Comprehensive Cancer Center at Seoul National University Bundang Hospital, overseeing multidisciplinary cancer care at one of South Korea's premier academic medical centres.
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International Research Exposure
Prof. Lee served as a Visiting Professor at MD Anderson Cancer Center (Department of Systems Biology, 2012โ€“2013), reflecting his engagement with global oncology research networks.
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Areas of Specialisation

Gastric, gastrointestinal, and head and neck cancer with systemic therapy and clinical trial expertise

Prof. Lee's clinical and research specialisation centres on gastrointestinal malignancies, including gastric, colorectal, and gastroesophageal junction cancers, alongside head and neck cancer. His practice integrates chemotherapy, early-phase clinical trials, and translational oncology research.

Treatment Specialties

Gastric & Gastroesophageal Junction Cancer

Systemic therapy and trial-based treatment for advanced and metastatic gastric and GEJ cancers.

starsChemotherapy & Combination Regimens
  • arrow_rightPlatinum- and fluoropyrimidine-based chemotherapy protocols
  • arrow_rightFOLFOX and mFOLFOX6 regimens for advanced gastric cancer
  • arrow_rightCombination cytotoxic regimens for locally advanced and metastatic disease
starsImmunotherapy Combinations
  • arrow_rightNivolumab plus chemotherapy in HER2-negative advanced gastric/GEJ cancer
  • arrow_rightTislelizumab plus chemotherapy (RATIONALE-305)
  • arrow_rightZanidatamab combined with tislelizumab and chemotherapy in HER2-positive GEJ adenocarcinoma
starsTargeted & Biomarker-Driven Therapy
  • arrow_rightBemarituzumab in FGFR2b-overexpressing gastric/GEJ cancer
  • arrow_rightHER2-targeted therapy combinations
  • arrow_rightBiomarker-guided treatment selection based on pathology and molecular profiling

Colorectal & Other GI Cancers

Medical oncology for colorectal cancer and other gastrointestinal malignancies.

starsColorectal Cancer Management
  • arrow_rightSystemic therapy planning for locally advanced and metastatic colorectal cancer
  • arrow_rightChemotherapy and targeted agent combinations
starsOther Gastrointestinal Malignancies
  • arrow_rightMedical oncology management of oesophageal and other GI cancers
  • arrow_rightMultidisciplinary evaluation and systemic treatment planning

Head & Neck Cancer

Systemic treatment and chemotherapy for head and neck malignancies.

starsSystemic Therapy for Head & Neck Cancer
  • arrow_rightChemotherapy-based treatment planning
  • arrow_rightMedical oncology support within a multidisciplinary care framework

Early-Phase Clinical Trials & Translational Research

Phase I/II oncology trials and translational biomarker research at SNUBH's Clinical Trial Center.

starsEarly-Phase Oncology Trials
  • arrow_rightPhase I and II trials in gastrointestinal cancers
  • arrow_rightFirst-line combination studies in gastric and GEJ adenocarcinoma
starsLiquid Biopsy & Biomarker Research
  • arrow_rightCirculating tumour DNA (ctDNA) analysis in gastric cancer
  • arrow_rightTranslational research on predictive and prognostic biomarkers
Clinical Focus Areas
check_circleAdvanced Gastric Cancer
check_circleGastroesophageal Junction Cancer
check_circleColorectal Cancer
check_circleHead & Neck Cancer
check_circleEarly-Phase Clinical Trials
check_circleTranslational & Biomarker Research
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Procedures Performed

Systemic treatment and clinical research services in gastrointestinal and head and neck oncology

Prof. Lee's procedural practice covers the full spectrum of medical oncology for gastric, colorectal, gastroesophageal junction, and head and neck cancers โ€” from chemotherapy administration to trial enrolment and translational research.

Chemotherapy Administration

Medical Oncology

Systemic chemotherapy protocols for gastric, colorectal, and other gastrointestinal cancers.

Chemotherapy Protocols
arrow_rightPlatinum- and fluoropyrimidine-based regimens (FOLFOX, mFOLFOX6)
arrow_rightPaclitaxel-based regimens for advanced gastric cancer
arrow_rightOxaliplatin and cisplatin combinations

Immunotherapy & Targeted Therapy

Targeted Therapy

Checkpoint inhibitor and molecularly targeted treatment combinations for eligible patients.

Immuno-Oncology Combinations
arrow_rightNivolumab plus chemotherapy for HER2-negative gastric/GEJ cancer
arrow_rightTislelizumab plus chemotherapy in first-line gastric adenocarcinoma
arrow_rightZanidatamab combined with immunotherapy and chemotherapy for HER2-positive disease
Biomarker-Guided Targeted Therapy
arrow_rightBemarituzumab for FGFR2b-overexpressing gastric/GEJ cancer
arrow_rightHER2-targeted agent combinations

Clinical Trial Enrolment & Management

Complex Disease

Early-phase and phase III oncology trial participation for eligible patients at the SNUBH Clinical Trial Center.

Phase I / II Trial Participation
arrow_rightScreening and enrolment for early-phase gastric and GI cancer trials
arrow_rightNovel agent combination studies
arrow_rightSafety and dose-escalation study management

Diagnostic Evaluation & Molecular Profiling

Diagnosis

Staging work-up and molecular profiling to guide systemic treatment selection.

Molecular Diagnostics
arrow_rightHER2 and FGFR2b IHC/FISH testing for gastric cancer
arrow_rightLiquid biopsy (ctDNA) for prognostic and predictive assessment
arrow_rightBiomarker-based treatment stratification

Second Opinion in Gastrointestinal Oncology

Second Opinion

Evidence-based review of cases and treatment plans for patients with gastric, colorectal, and GEJ cancers.

Case Review & Treatment Planning
arrow_rightReview of pathology reports, imaging, and prior treatment history
arrow_rightIndependent assessment of systemic therapy options and trial eligibility
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Research & Publications

Gastrointestinal oncology research, clinical trials, and translational science

Prof. Lee has published more than 300 peer-reviewed scientific articles with an h-index of 60 and over 18,000 citations (Scopus, as recorded by Seoul National University). His research focuses on gastric and gastroesophageal junction cancer, colorectal cancer, immunotherapy combinations, targeted therapy, and liquid biopsy.

Selected Recent Publications
arrow_rightNivolumab plus chemotherapy in HER2-negative, previously untreated, unresectable, advanced or recurrent gastric/gastroesophageal junction cancer โ€“ Gastric Cancer, 2024
arrow_rightTislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced gastric or gastro-oesophageal junction adenocarcinoma: RATIONALE-305 โ€“ BMJ, 2024
arrow_rightBemarituzumab plus mFOLFOX6 as first-line treatment in East Asian patients with FGFR2b-overexpressing locally advanced or metastatic gastric/gastroesophageal junction cancer โ€“ Gastric Cancer, 2024
arrow_rightLiquid Biopsy: An Emerging Diagnostic, Prognostic, and Predictive Tool in Gastric Cancer โ€“ Journal of Gastric Cancer, 2024
arrow_rightPhase Ib/II Study of Zanidatamab in Combination with Tislelizumab and Chemotherapy in First-Line HER2-Positive Gastric/Gastroesophageal Junction Adenocarcinoma โ€“ Clinical Cancer Research, 2026
Major Research Areas
arrow_rightGastric and gastroesophageal junction cancer โ€“ systemic therapy and survival outcomes
arrow_rightImmunotherapy combinations in first-line gastric adenocarcinoma
arrow_rightTargeted therapy in biomarker-selected gastric cancer populations
arrow_rightEarly-phase clinical trial design and execution in GI oncology
arrow_rightLiquid biopsy and circulating tumour DNA in gastric cancer
arrow_rightTranslational oncology and predictive biomarker research
Active Research Profile

Prof. Lee maintains an active publication record. A full list of his peer-reviewed papers is available through Seoul National University's research portal and PubMed.

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Education & Training

Prof. Lee trained entirely at Seoul National University, completing his M.D., M.S., and Ph.D. before pursuing clinical fellowship and subspecialty training in haematology-oncology.

Undergraduate
M.D.
Seoul National University College of Medicine
1992 โ€“ 1998
Residency
Residency, Internal Medicine
Seoul National University Hospital
2000 โ€“ 2004
Postgraduate
M.S., Internal Medicine
Seoul National University Graduate School
2004
Fellowship
Fellowship, Haematology-Oncology
Seoul National University Hospital
2004 โ€“ 2005
Doctoral
Ph.D., Molecular Oncology
Seoul National University Graduate School
2007
International Fellowship
Visiting Professor, Department of Systems Biology
MD Anderson Cancer Center
2012 โ€“ 2013
International academic exposure in translational oncology and systems biology research.
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Clinical Experience

Prof. Lee has spent his entire academic career at Seoul National University Bundang Hospital, progressing from clinical professor in 2005 to full professor in 2018, and assuming successive leadership roles including Chief of the Division of Haematology-Oncology, Chief Director of the Clinical Trial Center, and Chief Director of the Comprehensive Cancer Center.

Professor, Division of Hematology & Medical Oncology; Chief Director, Comprehensive Cancer Center; Chief Director, Clinical Trial Center
Seoul National University Bundang Hospital
Seoul National University College of Medicine
check_circleGastric and gastroesophageal junction cancer
check_circleColorectal and other GI malignancies
check_circleHead and neck cancer
check_circleEarly-phase clinical trial leadership
check_circleTranslational and biomarker research
check_circleMultidisciplinary cancer centre leadership
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Languages & International

Prof. Lee consults in the following languages.

๐Ÿ‡ฐ๐Ÿ‡ทKorean
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients consulting with Prof. Lee.

CancerFax can coordinate professional medical interpreter support for international patients requiring communication assistance.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Keun-Wook Lee

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Keun-Wook Lee's team โ€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history โ€” prepared as a structured clinical summary for Dr. Keun-Wook Lee's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Keun-Wook Lee before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Keun-Wook Lee's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Keun-Wook Lee's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Keun-Wook Lee's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Prof. Keun-Wook Lee

Prof. Lee specialises in gastrointestinal cancers โ€” including gastric cancer, gastroesophageal junction cancer, and colorectal cancer โ€” as well as head and neck cancer. His clinical and research work has a particular focus on advanced and metastatic gastric cancer, systemic therapy combinations, and biomarker-driven treatment selection.

Prof. Lee is based at Seoul National University Bundang Hospital (SNUBH) in Seongnam, South Korea. He is a Professor of Internal Medicine in the Division of Hematology and Medical Oncology, and currently serves as Chief Director of the Comprehensive Cancer Center and Chief Director of the Clinical Trial Center at SNUBH.

CancerFax can coordinate medical-report review and consultation support for international patients seeking an expert opinion from Prof. Lee at Seoul National University Bundang Hospital, subject to hospital availability and case acceptance. Please submit your reports through CancerFax for an initial review.

Submit your medical reports through CancerFax. The CancerFax team will review the documents, prepare the case for submission, and coordinate the next steps with the hospital, subject to availability and case suitability.

A second-opinion request can be submitted through CancerFax with the patient's pathology reports, imaging, treatment history, and relevant test results. Prof. Lee's expertise in gastric and gastrointestinal cancer treatment planning makes him particularly well-placed for complex second-opinion cases. The final format and availability depend on the doctor's institution.

Yes. Prof. Lee serves as Chief Director of the Clinical Trial Center at Seoul National University Bundang Hospital and his official hospital profile lists chemotherapy clinical trials and early-phase clinical trials among his core areas of work. His recent trial involvement includes studies of nivolumab, tislelizumab, bemarituzumab, and zanidatamab in gastric and gastroesophageal junction cancers. Trial eligibility is assessed on an individual basis by the treating team.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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