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John Maris
verifiedCancerFax Verified
schoolMD, University of Pennsylvania

Dr.Β JohnΒ Maris

BS, MD

Giulio D'Angio Chair in Neuroblastoma Research

corporate_fareChildren's Hospital of Philadelphia, USA

check_circleNeuroblastoma
check_circlePaediatric Oncology
check_circleCAR T-Cell Research
check_circleChildhood Solid Cancers
INSTITUTION
corporate_fareChildren's Hospital of Philadelphia
DEPARTMENT
sciencePaediatric Oncology
SPECIALTY
medical_servicesNeuroblastoma & Childhood Solid Cancers
LOCATION
location_onPhiladelphia, United States
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
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John Maris

BS, MD

Dr. John M. Maris is an internationally recognised paediatric oncologist and physician-scientist at Children's Hospital of Philadelphia (CHOP), one of the leading paediatric cancer centres in the United States. He holds the Giulio D'Angio Chair in Neuroblastoma Research and is Professor of Pediatrics at the Perelman School of Medicine, University of Pennsylvania.

With more than three decades of focused work on neuroblastoma, Dr. Maris has dedicated his career to understanding why neuroblastoma develops, why some tumours resist standard treatment, and how genomic and immunotherapy discoveries can be translated into better therapies for children. His laboratory has contributed substantially to identifying neuroblastoma susceptibility genes and molecular drivers of the disease. He co-heads the CHOP Pediatric Cancer Dream Team and leads or participates in several early-phase clinical trials for refractory neuroblastoma. Google Scholar lists more than 66,000 citations to his published work. Dr. Maris has mentored more than 100 trainees across research and clinical disciplines throughout his career.

workspace_premium30+Years Experience
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Visiting Days
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International Patients

CancerFax can coordinate medical-report review and consultation support for international families seeking a paediatric oncology opinion from Dr. Maris at Children's Hospital of Philadelphia, subject to hospital availability and case acceptance.

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Why Consider Dr. John M. Maris?

Families dealing with high-risk, relapsed, or refractory neuroblastoma seek Dr. Maris for his unparalleled depth in paediatric neuroblastoma research and his direct access to early-phase clinical trials at CHOP, one of the world's foremost paediatric cancer centres.

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Neuroblastoma Genetics Pioneer
Dr. Maris's laboratory has identified many of the currently known neuroblastoma susceptibility genes and contributed extensively to understanding molecular pathogenesis, directly informing precision treatment approaches.
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Fellow of the AACR Academy (2024)
Elected Fellow of the AACR Academy in 2024 in recognition of outstanding contributions to paediatric cancer research, joining one of oncology's most prestigious honorary bodies.
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Clinical Trial & Immunotherapy Leadership
Dr. Maris co-leads the Pediatric Cancer Dream Team and chairs the NCI Cancer Moonshot Pediatric Immunotherapy Discovery and Development Steering Committee, giving patients potential access to novel immunotherapy and CAR T-cell approaches.
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Physician-Scientist Model of Care
His practice combines direct patient care with active laboratory research and early-phase trial leadership, offering children with refractory neuroblastoma research-informed treatment planning under one team.
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Areas of Specialisation

Expert paediatric oncology care focused on neuroblastoma, childhood solid tumours, and translational research-driven treatment strategies

Dr. Maris's clinical and research specialisations span neuroblastoma biology, precision therapeutics, paediatric cancer genetics, and immunotherapy. His work bridges bench science and bedside care, with a particular emphasis on children whose disease has not responded to standard treatment.

Clinical & Research Specialties

Neuroblastoma

Comprehensive evaluation and research-driven management of neuroblastoma, including high-risk and refractory cases.

starsHigh-Risk Neuroblastoma
  • arrow_rightMultidisciplinary treatment planning for newly diagnosed high-risk disease
  • arrow_rightGenomic profiling and biomarker-guided treatment selection
  • arrow_rightAccess to early-phase clinical trials for eligible patients
starsRefractory & Relapsed Neuroblastoma
  • arrow_rightEvaluation for early-phase clinical trial eligibility
  • arrow_rightPrecision therapeutics based on molecular and genetic disease profile
  • arrow_rightResearch-informed second opinion for complex cases

Paediatric Cancer Genetics & Immunotherapy

Genomic-based risk assessment, susceptibility gene discovery, and immunotherapy target development for childhood cancers.

starsCancer Genetics & Susceptibility
  • arrow_rightFamily-based and genome-wide association approaches to neuroblastoma risk
  • arrow_rightIdentification of molecular drivers and therapeutic targets
starsImmunotherapy & CAR T-Cell Research
  • arrow_rightPeptide-centric CAR T-cell therapy development for neuroblastoma
  • arrow_rightAnti-GD2 antibody-based treatment research contributions
  • arrow_rightRadiopharmaceutical therapy preclinical development including MABG approaches
Clinical Focus Areas
check_circleNeuroblastoma
check_circleRefractory Neuroblastoma
check_circleChildhood Solid Cancers
check_circlePaediatric Cancer Genetics
check_circleEarly-Phase Clinical Trials
check_circlePaediatric Immunotherapy
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Procedures & Clinical Approaches

Paediatric oncology services and research-led treatment pathways at Children's Hospital of Philadelphia

Dr. Maris's clinical work encompasses direct patient care, multidisciplinary treatment planning, early-phase trial participation, and precision therapeutics for neuroblastoma and other childhood solid cancers. Specific treatment availability should be confirmed with CHOP for each patient.

Paediatric Oncology Consultation

Medical Oncology

Comprehensive evaluation and treatment planning for children with neuroblastoma and other solid tumours.

Consultation Services
arrow_rightInitial and second-opinion consultations for neuroblastoma
arrow_rightMolecular and genomic profiling-guided treatment planning
arrow_rightMultidisciplinary tumour board evaluation

Early-Phase Clinical Trials

Complex Disease

Access to novel investigational therapies for children with refractory or relapsed neuroblastoma through CHOP-led and collaborative early-phase trials.

Trial-Based Treatment Pathways
arrow_rightEligibility assessment for early-phase neuroblastoma trials
arrow_rightInvestigational immunotherapy protocols where eligible
arrow_rightCAR T-cell therapy research participation where applicable

Precision & Targeted Therapy Planning

Targeted Therapy

Genomic and biomarker-driven treatment selection for neuroblastoma and related childhood cancers.

Precision Treatment Approaches
arrow_rightBiomarker-guided systemic therapy selection
arrow_rightAnti-GD2 antibody-based treatment approaches
arrow_rightRadiopharmaceutical therapy evaluation where indicated

Second Opinion

Second Opinion

Expert review of diagnosis, pathology, and treatment plan for families seeking a specialist neuroblastoma second opinion from CHOP.

Second Opinion Services
arrow_rightPathology and imaging review for neuroblastoma diagnosis
arrow_rightAssessment of current treatment plan and alternatives
arrow_rightRecommendations for clinical trial eligibility where appropriate
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Research & Publications

Major contributions to neuroblastoma biology, genetics, immunotherapy, and precision paediatric oncology

Dr. Maris is among the most cited paediatric oncology researchers globally, with over 66,000 citations recorded on Google Scholar. His work spans neuroblastoma susceptibility genetics, molecular pathogenesis, immunotherapy target discovery, CAR T-cell therapy development, and early-phase trial leadership.

Selected Peer-Reviewed Publications
arrow_rightRecent Advances in Neuroblastoma β€” New England Journal of Medicine, 2010 (widely cited review of neuroblastoma biology, clinical behaviour, and therapeutic advances)
arrow_rightContributions to neuroblastoma susceptibility gene discovery using family-based and genome-wide association approaches
arrow_rightResearch into molecular pathogenesis and therapeutic target identification in neuroblastoma
arrow_rightPreclinical work on radiopharmaceutical therapy for neuroblastoma, including MABG-based approaches
arrow_rightPeptide-centric CAR T-cell therapy research for neuroblastoma and other childhood cancers
Clinical Trials & National Leadership
arrow_rightCo-leader, Childhood Cancer Data Initiative Open Targets Project
arrow_rightChair, NCI Cancer Moonshot Pediatric Immunotherapy Discovery and Development Steering Committee
arrow_rightMember, NCI Cancer Moonshot Blue Ribbon Panel, Pediatric Cancer Working Group
arrow_rightChair, Children's Oncology Group Neuroblastoma Disease Committee (2006–2010)
arrow_rightCo-head, Pediatric Cancer Dream Team, Children's Hospital of Philadelphia
Research Profile

Dr. Maris's full publication list is available on Google Scholar and PubMed. His laboratory continues to publish actively on neuroblastoma genetics, immunotherapy, and precision therapeutics.

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Education & Training

Dr. Maris completed his undergraduate studies at Wheeling College, earned his MD at the University of Pennsylvania School of Medicine, and completed specialist training in paediatric haematology/oncology and cancer genetics entirely at Children's Hospital of Philadelphia.

Undergraduate
BS, Biology
Wheeling College
1983
Medical Degree
MD, Medicine
University of Pennsylvania School of Medicine
1989
Residency
Residency, Paediatrics
Children's Hospital of Philadelphia / University of Pennsylvania
1989 – 1992
Fellowship
Fellowship, Paediatric Haematology/Oncology
Children's Hospital of Philadelphia
1992 – 1995
Postdoctoral Training
Postdoctoral Fellowship, Cancer Genetics
Children's Hospital of Philadelphia
1995 – 1996
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Clinical Experience

Dr. Maris has spent his entire clinical and research career at Children's Hospital of Philadelphia, progressing from trainee to one of the most prominent paediatric cancer physician-scientists in the United States. He currently serves as Attending Physician, holds the Giulio D'Angio Chair in Neuroblastoma Research, and directs the Center for Childhood Cancer Research.

Giulio D'Angio Chair in Neuroblastoma Research; Attending Physician
Children's Hospital of Philadelphia
Center for Childhood Cancer Research; Perelman School of Medicine, University of Pennsylvania
check_circleNeuroblastoma clinical care and early-phase trials
check_circlePaediatric cancer genetics and susceptibility research
check_circleImmunotherapy and CAR T-cell target development
check_circleNational and international paediatric oncology trial leadership
check_circleMentorship of more than 100 clinical and research trainees
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Languages & International

Dr. Maris consults in English. No other languages have been publicly confirmed from reviewed sources.

πŸ‡ΊπŸ‡ΈEnglish
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients consulting through Children's Hospital of Philadelphia.

CancerFax can coordinate professional medical interpreter support for international families when required.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. John Maris

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. John Maris's team β€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history β€” prepared as a structured clinical summary for Dr. John Maris's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. John Maris before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. John Maris's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. John Maris's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. John Maris's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Dr. John M. Maris

Dr. Maris specialises in paediatric oncology with a primary focus on neuroblastoma and childhood solid cancers. Children's Hospital of Philadelphia lists neuroblastoma and childhood solid tumours as his core areas of clinical expertise, encompassing both newly diagnosed and refractory disease.

Dr. John M. Maris is an Attending Physician at Children's Hospital of Philadelphia (CHOP) in the United States, where he also holds the Giulio D'Angio Chair in Neuroblastoma Research and directs the Center for Childhood Cancer Research. He is additionally Professor of Pediatrics at the Perelman School of Medicine, University of Pennsylvania.

Children's Hospital of Philadelphia has pathways for new patient referrals and second opinions, including for international families. CancerFax can help coordinate medical-report preparation and submission to CHOP, subject to hospital availability and case acceptance. Families should confirm appointment eligibility directly with CHOP.

A second-opinion request for neuroblastoma or another childhood solid tumour can be submitted through CancerFax. You will need to provide pathology reports, imaging, treatment history, and any relevant genomic or biomarker results. The final consultation format and availability are subject to the doctor's schedule and CHOP's institutional policies.

Yes. Dr. Maris is an active clinical trial leader. His clinical practice includes caring for children with refractory neuroblastoma, often within early-phase clinical trials. He co-leads the Pediatric Cancer Dream Team and chairs the NCI Cancer Moonshot Pediatric Immunotherapy Discovery and Development Steering Committee. Trial eligibility must be assessed individually by the CHOP team.

Submit your child's medical reports through CancerFax. The CancerFax team will review the documents, prepare the case summary, and coordinate the next steps with Children's Hospital of Philadelphia, subject to availability and case-acceptance criteria. You can begin by uploading reports at cancerfax.com.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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