Dr.ย Jacobย Gopas
PhD (Doctor of Philosophy)
Professor, Department of Microbiology and Immunology
corporate_fareBen-Gurion University of the Negev / Soroka Medical Center, Beer-Sheva
Jacob Gopas
PhD (Doctor of Philosophy)
Prof. Jacob Gopas is a Professor in the Shraga Segal Department of Microbiology and Immunology at Ben-Gurion University of the Negev in Beer-Sheva, Israel, with a joint affiliation at Soroka University Medical Center. He is a specialist in cancer immunology, tumour biology, and translational oncology, with more than three decades of research focused on the NF-kB signalling pathway, Hodgkin's lymphoma biology, and mechanisms of drug resistance in cancer.
Prof. Gopas completed his PhD at the Albert Einstein College of Medicine in New York, where his doctoral research centred on MHC immunogenetics. After postdoctoral work at Ben-Gurion University's Faculty of Health Sciences, he established his own laboratory and research programme at BGU. His research spans the identification and characterisation of NF-kB inhibitors from natural sources with potential anti-cancer, anti-inflammatory, and antiviral applications; the biology of Hodgkin's lymphoma including the role of the measles virus in tumour cells; mechanisms of drug resistance in melanoma cell lines; and the tumour microenvironment's role in platinum chemoresistance in ovarian cancer. His laboratory works in close collaboration with clinical colleagues at Soroka University Medical Center, providing a translational bridge between laboratory discovery and patient care.
CancerFax can assist international patients and referring physicians in accessing expert oncology consultation and clinical trial evaluation at institutions affiliated with Prof. Gopas's programme in Beer-Sheva, subject to availability and case suitability.
Why Consider Prof. Jacob Gopas?
Prof. Gopas is one of Israel's most experienced cancer immunology researchers, combining deep mechanistic expertise with clinical translation through his long-standing collaboration with Soroka University Medical Center.
Areas of Research Specialisation
Cancer immunology, NF-kB biology, lymphoma, and tumour drug resistance
Prof. Gopas's research programme covers cancer immunology, the NF-kB signalling pathway, Hodgkin's lymphoma biology, drug resistance in melanoma and ovarian cancer, and the development of natural anti-cancer compounds. His work is fundamentally translational โ bridging laboratory discovery with clinical relevance through collaboration with Soroka University Medical Center.
NF-kB Pathway in Cancer
Mechanistic and applied research into the NF-kB transcription factor as a driver of cancer, inflammation, and chemotherapy resistance.
- arrow_rightDetection and characterisation of natural compounds that inhibit NF-kB activity
- arrow_rightInvestigation of NF-kB-mediated drug resistance in cancer cell lines
- arrow_rightAnti-inflammatory and anti-viral properties of NF-kB inhibitors from plant extracts
- arrow_rightStudy of chronic inflammation as a promoter of cancer initiation and progression
- arrow_rightMechanisms by which inflammatory signals render tumour cells resistant to chemotherapy
Hodgkin's Lymphoma Biology
Long-standing translational research programme into the biological drivers of Hodgkin's lymphoma, conducted in collaboration with Soroka University Medical Center.
- arrow_rightPioneering study demonstrating measles virus proteins in Hodgkin's lymphoma tumour cells
- arrow_rightEpidemiological and laboratory research on viral associations with classical HL
- arrow_rightInvestigation of cellular senescence mechanisms in HL tumour biology
- arrow_rightCollaborative research with BGU and international partners on HL tumour microenvironment
Drug Resistance in Solid Tumours
Research into mechanisms by which tumour cells evade chemotherapy, with implications for melanoma and ovarian cancer treatment.
- arrow_rightIn-vitro selection and characterisation of drug-resistant melanoma cell lines
- arrow_rightMechanistic studies on resistance pathways relevant to clinical melanoma treatment
- arrow_rightTumour microenvironment-mediated platinum resistance in ovarian cancer
- arrow_rightIdentification of soluble factors from tumour-activated mesenchymal stromal cells conferring cisplatin resistance
- arrow_rightInvestigation of flavonoids and kinase inhibitors to restore platinum sensitivity
Research & Clinical Translation Services
Translational oncology research, clinical collaboration, and expert consultation
Prof. Gopas's primary role is as a translational researcher. His relevance to patients lies in his scientific contributions to understanding cancer mechanisms and his collaboration with clinical colleagues at Soroka University Medical Center. CancerFax can help coordinate access to oncology services and clinical trial evaluation at affiliated institutions.
Translational Cancer Research Consultation
Complex DiseaseExpert scientific input on cancer immunology, NF-kB pathway involvement, drug resistance mechanisms, and novel therapeutic strategies, in collaboration with clinical teams.
Clinical Trial Access via Soroka Medical Center
Medical OncologyPatients with lymphoma, melanoma, solid tumours, or ovarian cancer may be eligible for investigational programmes linked to Prof. Gopas's translational research at Soroka University Medical Center.
Expert Second Opinion โ Lymphoma & Solid Tumours
Second OpinionScientific and clinical expert input for complex cases involving Hodgkin's lymphoma, drug-resistant melanoma, or ovarian cancer, coordinated through CancerFax and affiliated clinical colleagues.
Multidisciplinary Oncology Review
MultidisciplinaryCoordinated review integrating Prof. Gopas's laboratory expertise with Soroka Medical Center's clinical oncology, pathology, and haematology services.
Research & Publications
Peer-reviewed contributions in cancer immunology, lymphoma, and NF-kB biology
Prof. Gopas has an active publication record in cancer immunology, translational oncology, and molecular biology. His research group at Ben-Gurion University has contributed to understanding of NF-kB-driven drug resistance, Hodgkin's lymphoma tumour biology, and novel natural compounds with anti-cancer potential.
Prof. Gopas's publications are indexed on ResearchGate and PubMed. A detailed research summary is available on request through CancerFax.
Education & Training
Prof. Gopas completed his undergraduate medical and science training in Israel before obtaining his PhD at the Albert Einstein College of Medicine in New York, with doctoral research in cellular immunology and MHC genetics. He completed postdoctoral work at Ben-Gurion University and later added a Master's in Health Management.
Clinical Experience
Prof. Gopas has spent his career at Ben-Gurion University of the Negev, where he established and leads a translational cancer immunology laboratory in the Shraga Segal Department of Microbiology and Immunology, with close clinical ties to Soroka University Medical Center.
Languages & International
Prof. Gopas consults and communicates in the following languages.
CancerFax can coordinate professional medical interpreter support for international patients requiring assistance in languages beyond those listed.
CancerFax can coordinate professional medical interpreter support for additional languages when required.
How CancerFax Helps You Access Dr. Jacob Gopas
CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Jacob Gopas's team โ with full coordination from initial inquiry to consultation.
Medical Report Review
Free review of your pathology results, imaging, molecular profiling, and treatment history โ prepared as a structured clinical summary for Dr. Jacob Gopas's team.
Treatment Eligibility Screening
CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Jacob Gopas before you travel, so you arrive with a clear pathway.
Case Submission
We coordinate direct case submission to Dr. Jacob Gopas's department, including all documentation required for clinical review and appointment scheduling.
Appointment & Consultation Coordination
CancerFax manages appointment scheduling with Dr. Jacob Gopas's team, confirming availability and aligning timelines with your travel plans.
Travel, Visa & Logistics Support
We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.
Follow-Up & Continuity of Care
After your consultation or treatment, CancerFax facilitates communication between Dr. Jacob Gopas's team and your home oncologist for seamless post-treatment follow-up.
Frequently Asked Questions About Prof. Jacob Gopas
Prof. Jacob Gopas is a Professor in the Shraga Segal Department of Microbiology and Immunology at Ben-Gurion University of the Negev in Beer-Sheva, Israel. He is a specialist in cancer immunology and translational oncology, with over 30 years of research focused on NF-kB signalling pathways, Hodgkin's lymphoma biology, drug resistance in melanoma and ovarian cancer, and natural anti-cancer compounds.
NF-kB is a family of transcription factors that regulate immune responses and inflammation. In cancer, abnormal NF-kB activation can drive tumour growth, promote cancer cell survival, and cause resistance to chemotherapy. Prof. Gopas's research group has focused extensively on identifying natural and synthetic compounds that inhibit this pathway, with potential implications for treating lymphoma, solid tumours, and drug-resistant cancers.
CancerFax can assist international patients in coordinating access to oncology consultation and clinical evaluation at institutions affiliated with Prof. Gopas's translational research programme, including Soroka University Medical Center in Beer-Sheva. Please submit your medical reports through CancerFax to begin the coordination process, subject to availability and case suitability.
Prof. Gopas's research programme covers Hodgkin's lymphoma, melanoma, ovarian cancer, and other solid tumours involving NF-kB pathway activation or inflammation-driven mechanisms. His translational work has particular relevance for patients with drug-resistant cancers or those being evaluated for novel therapeutic approaches.
Prof. Gopas's translational research at Ben-Gurion University informs clinical investigation at Soroka University Medical Center. Patients with lymphoma, ovarian cancer, or melanoma may be eligible for studies aligned with his research programme. Specific trial availability depends on current study status and individual patient eligibility. CancerFax can help coordinate an initial enquiry.
A second-opinion request for cases involving lymphoma, melanoma, or ovarian cancer can be submitted through CancerFax with relevant pathology reports, imaging, and treatment history. Expert input drawing on Prof. Gopas's translational expertise and clinical colleagues at Soroka Medical Center can be explored, subject to institutional availability and case acceptance.
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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.