
Dr.Β EileenΒ O'Reilly
MB BCh BAO, MD
Section Head, Hepatopancreaticobiliary & Neuroendocrine Cancers
corporate_fareMemorial Sloan Kettering Cancer Center, New York
Eileen O'Reilly
MB BCh BAO, MD
Dr. Eileen M. O'Reilly is a medical oncologist at Memorial Sloan Kettering Cancer Center in New York, where she serves as Section Head for Hepatopancreaticobiliary and Neuroendocrine Cancers. She holds the Winthrop Rockefeller Endowed Chair in Medical Oncology and is Co-Director for Medical Initiatives at the David M. Rubenstein Center for Pancreatic Cancer. She is also Professor of Medicine at Weill Cornell Medical College.
Dr. O'Reilly received her medical degree from Trinity College, Dublin University in 1990, completed postgraduate training in Ireland, and then undertook Haematology/Oncology fellowship training at Memorial Sloan Kettering. Her clinical practice centres on pancreatic cancer, liver cancer, bile duct cancer, gallbladder cancer, and other gastrointestinal malignancies. She leads multiple NCI-funded clinical trials and co-directs the MSK pancreatic cancer SPORE programme, with research spanning gene-based treatments, immunotherapy including vaccine-based strategies, and molecularly targeted personalised therapy. She has authored and co-authored more than 500 peer-reviewed articles, editorials, and book chapters, and serves as Senior or Associate Editor for the Journal of Clinical Oncology and Clinical Cancer Research. Her national leadership includes Co-Chair of the NCI Alliance Cooperative Group Gastrointestinal Cancers Committee and membership of the NCI Gastrointestinal Cancers Steering Committee.
CancerFax can coordinate medical-report review and consultation support for international patients seeking an opinion from specialists at Memorial Sloan Kettering Cancer Center.
Why Consider Dr. Eileen O'Reilly?
Dr. O'Reilly is one of the most published and nationally recognised experts in pancreatic and hepatobiliary oncology, combining active clinical trial leadership with multidisciplinary patient care at one of the world's leading cancer centres.
Areas of Specialisation
Pancreatic, hepatobiliary, neuroendocrine, and gastrointestinal cancers with a focus on molecularly guided and trial-based treatment
Dr. O'Reilly's clinical and research specialisation centres on pancreatic cancer and hepatobiliary malignancies, with expertise in immunotherapy, vaccine-based strategies, gene-based treatments, and personalised targeted approaches driven by each patient's molecular tumour profile.
Pancreatic Cancer
Comprehensive medical oncology for pancreatic adenocarcinoma and related pancreatic malignancies, including advanced systemic therapy and clinical trial access.
- arrow_rightChemotherapy regimens including FOLFIRINOX and gemcitabine-based protocols
- arrow_rightAdjuvant and neoadjuvant treatment planning
- arrow_rightBiomarker-guided therapy selection including BRCA-directed approaches
- arrow_rightKRAS-targeted vaccine strategies in clinical trials
- arrow_rightGene-based and immunotherapy trial access through MSK SPORE programme
- arrow_rightRAS-directed targeted therapy including investigational agents
Hepatobiliary & GI Cancers
Medical oncology for liver cancer, bile duct cancer, gallbladder cancer, and other gastrointestinal malignancies.
- arrow_rightHepatocellular carcinoma and intrahepatic cholangiocarcinoma
- arrow_rightBile duct and gallbladder cancer treatment planning
- arrow_rightSystemic therapy and trial participation for hepatobiliary cancers
- arrow_rightPancreatic and gastrointestinal neuroendocrine tumours
- arrow_rightGastric, colorectal, and other gastrointestinal malignancies
- arrow_rightMultidisciplinary treatment planning for complex GI cases
Immunotherapy & Personalised Oncology
Research-driven immunotherapy, vaccine-based strategies, and molecularly targeted treatment selection.
- arrow_rightCheckpoint inhibitor therapy for eligible patients
- arrow_rightVaccine-based immunotherapy in clinical trials for pancreatic and colorectal cancers
- arrow_rightBRCA and PALB2-directed targeted therapy including olaparib for eligible patients
- arrow_rightBiomarker-driven treatment selection based on next-generation sequencing
- arrow_rightPersonalised therapy based on molecular tumour profiling
Procedures Performed
Medical oncology services, systemic therapy, and clinical trial access for pancreatic and gastrointestinal cancers
As a medical oncologist, Dr. O'Reilly's clinical services encompass systemic cancer treatment, personalised molecularly guided therapy, and access to investigational treatments through NCI-funded clinical trials at MSK.
Pancreatic Cancer Treatment
Medical OncologyComprehensive systemic treatment planning for pancreatic adenocarcinoma across all stages, including adjuvant, neoadjuvant, and metastatic settings.
Targeted & Biomarker-Guided Therapy
Targeted TherapyPersonalised treatment selection based on tumour molecular profiling and germline testing results.
Hepatobiliary Cancer Treatment
Medical OncologySystemic treatment planning for liver cancer, bile duct cancer, gallbladder cancer, and related malignancies.
Clinical Trial Access
Complex DiseaseAccess to NCI-funded investigational protocols for pancreatic and gastrointestinal cancers through the MSK SPORE programme and cooperative group trials.
Second Opinion β Pancreatic & GI Cancers
Second OpinionExpert second-opinion evaluation for patients with pancreatic, hepatobiliary, and gastrointestinal malignancies.
Research & Publications
500+ peer-reviewed publications and NCI-funded clinical trial leadership in pancreatic and GI oncology
Dr. O'Reilly is one of the most published clinical investigators in pancreatic and hepatobiliary oncology. Her research focuses on drug development for pancreatic cancer, molecularly guided therapy, immunotherapy and vaccine approaches, KRAS-targeted strategies, and biomarker-based treatment selection.
Dr. O'Reilly's complete publication list and trial portfolio is available through her MSK profile and Google Scholar page. CancerFax can help coordinate access for case review.
Education & Training
Dr. O'Reilly received her medical degree from Trinity College, Dublin University in Ireland in 1990 and subsequently completed fellowship training in Haematology and Oncology at Memorial Sloan Kettering Cancer Center in New York.
Clinical Experience
Dr. O'Reilly has spent the majority of her career at Memorial Sloan Kettering Cancer Center, where she has risen to lead the Hepatopancreaticobiliary and Neuroendocrine Cancers section within the Gastrointestinal Oncology Service. She holds one of MSK's most distinguished endowed chairs and co-directs the institution's dedicated pancreatic cancer research centre.
Languages & International
Dr. O'Reilly consults in the following language.
CancerFax can coordinate professional medical interpreter support for international patients consulting at Memorial Sloan Kettering Cancer Center.
CancerFax can coordinate professional medical interpreter support for international patients where required.
How CancerFax Helps You Access Dr. Eileen O'Reilly
CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Eileen O'Reilly's team β with full coordination from initial inquiry to consultation.
Medical Report Review
Free review of your pathology results, imaging, molecular profiling, and treatment history β prepared as a structured clinical summary for Dr. Eileen O'Reilly's team.
Treatment Eligibility Screening
CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Eileen O'Reilly before you travel, so you arrive with a clear pathway.
Case Submission
We coordinate direct case submission to Dr. Eileen O'Reilly's department, including all documentation required for clinical review and appointment scheduling.
Appointment & Consultation Coordination
CancerFax manages appointment scheduling with Dr. Eileen O'Reilly's team, confirming availability and aligning timelines with your travel plans.
Travel, Visa & Logistics Support
We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.
Follow-Up & Continuity of Care
After your consultation or treatment, CancerFax facilitates communication between Dr. Eileen O'Reilly's team and your home oncologist for seamless post-treatment follow-up.
Frequently Asked Questions About Dr. Eileen O'Reilly
Dr. O'Reilly specialises in pancreatic cancer, liver cancer, bile duct cancer (cholangiocarcinoma), gallbladder cancer, neuroendocrine tumours, and other gastrointestinal malignancies. Her primary clinical and research focus is pancreatic cancer.
Dr. O'Reilly is an Attending Physician and Section Head at Memorial Sloan Kettering Cancer Center in New York, United States. She is also Professor of Medicine at Weill Cornell Medical College.
Memorial Sloan Kettering Cancer Center has established pathways for international patients. CancerFax can help coordinate medical-report review and consultation support for patients outside the United States seeking an opinion from Dr. O'Reilly, subject to hospital availability and case acceptance.
You can submit your medical reports, pathology, and imaging through CancerFax. The CancerFax team will review your documents, prepare the case summary, and coordinate the next steps with Memorial Sloan Kettering, subject to the hospital's availability and appointment processes.
Dr. O'Reilly leads multiple NCI-funded clinical trials through the MSK pancreatic cancer SPORE programme and serves as Co-Chair of the NCI Alliance Cooperative Group Gastrointestinal Cancers Committee. Her active trial interests include KRAS-targeted vaccine strategies, RAS-directed agents, and biomarker-driven protocols for pancreatic and hepatobiliary cancers. Eligibility for any specific trial is assessed by the treating team at MSK.
Dr. O'Reilly's practice includes molecularly guided treatment selection based on next-generation sequencing and germline testing. This includes BRCA-directed therapy such as olaparib for eligible patients with germline BRCA-mutated metastatic pancreatic cancer, KRAS-targeted investigational approaches in clinical trials, and immunotherapy strategies for selected patients.
Connect with Eileen O'Reilly Today
Share your medical reports for a free preliminary review. Our patient coordinators will help you understand your options and arrange a direct consultation.
Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.