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David Maloney
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schoolMD, PhD – Stanford University

Dr.Β DavidΒ Maloney

MD, PhD

Professor Emeritus, Translational Science & Therapeutics

corporate_fareFred Hutchinson Cancer Center, Seattle

check_circleCAR T-Cell Therapy
check_circleLymphoma & Leukaemia
check_circleCancer Immunotherapy
check_circleMultiple Myeloma
INSTITUTION
corporate_fareFred Hutchinson Cancer Center
DEPARTMENT
scienceTranslational Science & Therapeutics
SPECIALTY
medical_servicesCAR T-Cell Therapy & Blood Cancer Immunotherapy
LOCATION
location_onSeattle, United States
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
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David Maloney

MD, PhD

Dr. David G. Maloney is a physician-scientist at Fred Hutchinson Cancer Center, Seattle, recognised internationally for his contributions to CAR T-cell therapy, monoclonal antibody therapy, and hematopoietic cell transplantation for blood cancers. He holds an MD and PhD from Stanford University and has more than four decades of clinical and research experience in haematologic oncology.

Dr. Maloney's career has centred on developing safer and more effective immune-based therapies for patients with lymphoma, leukaemia, chronic lymphocytic leukaemia, non-Hodgkin lymphoma, and multiple myeloma. He was instrumental in the development and clinical testing of rituximab β€” the first antibody-based cancer drug to reach the market β€” which transformed treatment for B-cell malignancies. He subsequently helped establish the Bezos Family Immunotherapy Clinic at Fred Hutch and served as its first medical director, overseeing the delivery of genetically engineered immune cell therapies including CAR T-cell products. He has authored more than 200 peer-reviewed publications and has led multiple clinical trials in cellular immunotherapy and reduced-intensity transplantation. His current academic role is Professor Emeritus in the Translational Science and Therapeutics Division and a member of the Immunotherapy Integrated Research Center at Fred Hutch.

workspace_premium41+Years Experience
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Visiting Days
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International Patient Coordination

CancerFax can coordinate medical-report review and consultation support for international patients seeking an expert opinion from Dr. Maloney at Fred Hutchinson Cancer Center, subject to appointment availability and case acceptance.

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Why Consider Dr. David Maloney?

Dr. Maloney is a globally recognised pioneer in blood cancer immunotherapy, with landmark contributions to rituximab, CAR T-cell therapy, and reduced-intensity transplantation that continue to shape standard-of-care treatment worldwide.

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Pioneer of Rituximab
Fred Hutch credits Dr. Maloney with instrumental work in the development and clinical testing of rituximab, the first antibody-based cancer drug to reach the market, transforming treatment for B-cell leukaemias and lymphomas.
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CAR T-Cell Therapy Leadership
He served as the founding medical director of the Bezos Family Immunotherapy Clinic at Fred Hutch, leading the clinical delivery of CAR T-cell therapies for patients with relapsed or refractory blood cancers.
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200+ Peer-Reviewed Publications
With more than 200 published papers and multiple clinical trial leadership roles, Dr. Maloney brings an evidence base spanning cellular immunotherapy, antibody therapy, and hematopoietic cell transplantation.
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Klorfine Endowed Chair Recipient
He was the first recipient of the Leonard and Norma Klorfine Endowed Chair for Clinical Research at Fred Hutchinson Cancer Research Center in 2016, recognising his contribution to cancer immunotherapy.
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Areas of Specialisation

Advanced immune-based therapies for haematologic malignancies

Dr. Maloney's clinical and research expertise covers the full spectrum of immune-based and cellular therapies for blood cancers, with particular depth in CAR T-cell therapy, antibody-based treatments, and hematopoietic cell transplantation.

Clinical Specialties

CAR T-Cell & Cellular Immunotherapy

Genetically engineered immune cell therapies for relapsed or refractory haematologic malignancies.

starsCAR T-Cell Therapy
  • arrow_rightCAR T-cell therapy for eligible patients with leukaemia, lymphoma, and myeloma
  • arrow_rightPatient selection, pre-infusion conditioning, and post-infusion monitoring
  • arrow_rightClinical trial–based access to novel CAR T constructs
starsCancer Immunotherapy
  • arrow_rightMonoclonal antibody therapy including rituximab-based regimens
  • arrow_rightAntibody-drug conjugates and radioimmunotherapy approaches
  • arrow_rightGraft-versus-tumour immune effect optimisation in transplant settings

Hematopoietic Cell Transplantation

Autologous and allogeneic transplant strategies, including reduced-intensity conditioning regimens.

starsAllogeneic & Autologous Transplantation
  • arrow_rightAllogeneic stem cell transplantation for haematologic malignancies
  • arrow_rightAutologous stem cell transplantation for eligible patients
  • arrow_rightReduced-intensity and nonmyeloablative conditioning regimens for CLL, NHL, and myeloma
starsTransplant Immune Optimisation
  • arrow_rightStrategies to preserve graft-versus-tumour immunity
  • arrow_rightReduction of graft-versus-host disease complications
  • arrow_rightPost-transplant immune reconstitution monitoring

Lymphoma, Leukaemia & Myeloma

Specialist management of B-cell and other haematologic malignancies.

starsLymphoma & CLL
  • arrow_rightNon-Hodgkin lymphoma β€” B-cell subtypes including DLBCL and follicular lymphoma
  • arrow_rightChronic lymphocytic leukaemia β€” treatment planning for relapsed and refractory cases
  • arrow_rightAntibody and cellular therapy integration into lymphoma management
starsMultiple Myeloma
  • arrow_rightMyeloma management including transplant-eligible and transplant-ineligible pathways
  • arrow_rightCAR T-cell and antibody-based approaches for relapsed myeloma
Clinical Focus Areas
check_circleCAR T-Cell Therapy
check_circleLymphoma & Non-Hodgkin Lymphoma
check_circleChronic Lymphocytic Leukaemia
check_circleMultiple Myeloma
check_circleHematopoietic Cell Transplantation
check_circleMonoclonal Antibody Therapy
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Procedures & Treatment Approaches

Clinical services in cellular immunotherapy and blood cancer treatment

Dr. Maloney's clinical practice encompasses the full range of immune-based and transplant-based treatments for haematologic malignancies, from CAR T-cell infusion and stem cell transplantation to antibody therapy and clinical trial enrolment.

CAR T-Cell & Cellular Immunotherapy

Medical Oncology

Delivery and oversight of genetically engineered immune cell therapies for eligible blood cancer patients.

CAR T-Cell Treatment
arrow_rightPatient eligibility assessment for CAR T-cell therapy
arrow_rightPre-infusion conditioning chemotherapy
arrow_rightCAR T-cell infusion and in-patient monitoring
arrow_rightPost-infusion immune response and toxicity management

Hematopoietic Cell Transplantation

Transplant

Autologous and allogeneic transplant programmes with a focus on reduced-intensity conditioning for older or less fit patients.

Transplant Procedures
arrow_rightAutologous stem cell transplantation
arrow_rightAllogeneic stem cell transplantation (matched related and unrelated donors)
arrow_rightReduced-intensity / nonmyeloablative conditioning regimens
arrow_rightRadioimmunotherapy-based transplant conditioning

Antibody-Based Cancer Therapy

Targeted Therapy

Monoclonal antibody and antibody-drug conjugate protocols for B-cell malignancies and selected other cancers.

Antibody Therapy Approaches
arrow_rightRituximab-based combination regimens for B-cell lymphoma and CLL
arrow_rightAntibody-drug conjugate protocols where applicable
arrow_rightRadioactive antibody delivery to targeted tumour cells

Post-Treatment Monitoring

Monitoring

Ongoing disease surveillance and immune reconstitution assessment following cellular or transplant therapy.

Monitoring & Follow-Up
arrow_rightMinimal residual disease (MRD) monitoring post-transplant
arrow_rightImmune reconstitution assessment after CAR T-cell therapy
arrow_rightLong-term remission surveillance for lymphoma and myeloma

Second Opinion Consultations

Second Opinion

Independent expert review of diagnosis and treatment planning for patients with complex or relapsed haematologic cancers.

Second Opinion Process
arrow_rightReview of pathology, bone marrow biopsy, and molecular profiling reports
arrow_rightAssessment of prior treatment history and response
arrow_rightEvaluation of CAR T-cell, transplant, or trial eligibility
arrow_rightWritten expert opinion on alternative treatment pathways
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Research & Publications

Landmark contributions to cancer immunotherapy and haematologic oncology

Dr. Maloney has authored more than 200 peer-reviewed publications and led multiple clinical trials in cellular immunotherapy, antibody therapy, and hematopoietic cell transplantation. His work spans foundational discoveries with rituximab to contemporary CAR T-cell therapy programmes.

Peer-Reviewed Publications
arrow_rightDevelopment and clinical testing of rituximab β€” the first antibody-based cancer drug to reach the market (Fred Hutch, multiple publications)
arrow_rightReduced-intensity nonmyeloablative conditioning regimens for CLL, non-Hodgkin lymphoma, and myeloma (Fred Hutch publications)
arrow_rightGraft-versus-tumour immune effects and strategies to reduce graft-versus-host disease (Fred Hutch publications)
arrow_rightMore than 200 peer-reviewed publications across cellular immunotherapy, antibody therapy, and transplantation (A2 Biotherapeutics profile)
Clinical Trial Leadership
arrow_rightPrincipal investigator β€” NCT02706392: Genetically Modified T-Cell Therapy in Advanced ROR1-Positive Malignancies (Fred Hutch / ClinicalTrials.gov)
arrow_rightMultiple clinical trials in CAR T-cell therapy for leukaemia, lymphoma, and myeloma led through the Bezos Family Immunotherapy Clinic, Fred Hutch
Awards & Recognition
arrow_rightFirst recipient of the Leonard and Norma Klorfine Endowed Chair for Clinical Research, Fred Hutchinson Cancer Research Center, 2016
arrow_rightPresidential Award, International Society for Biological Therapy of Cancer (now Society for Immunotherapy of Cancer), 1993
Clinical Trial Access

Dr. Maloney has led clinical trials at Fred Hutch in CAR T-cell therapy and cellular immunotherapy. CancerFax can help assess whether a patient may be eligible for open studies, subject to institutional review.

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Education & Training

Dr. Maloney trained at Whitworth College and Stanford University, completing his MD and PhD in Cancer Biology at Stanford before undertaking residency and fellowship training at Brigham and Women's Hospital and Stanford.

Undergraduate
BS, Chemistry
Whitworth College, Spokane, Washington
1973 – 1977
Medical Degree
MD
Stanford University School of Medicine
1981 – 1985
Doctor of Medicine from one of the leading medical schools in the United States.
Residency
Internal Medicine Residency
Brigham and Women's Hospital, Boston
1985 – 1988
Fellowship
Medical Oncology Fellowship
Stanford University
1988 – 1994
Doctoral Degree
PhD, Cancer Biology
Stanford University
1991
Doctoral research in cancer biology, providing the scientific foundation for his subsequent translational immunotherapy work.
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Clinical Experience

Dr. Maloney has spent the majority of his career at Fred Hutchinson Cancer Center, where he rose to full professor, led the cellular immunotherapy programme, and established the Bezos Family Immunotherapy Clinic before transitioning to his current role as Professor Emeritus.

Professor Emeritus, Translational Science & Therapeutics Division
Fred Hutchinson Cancer Center
Immunotherapy Integrated Research Center
check_circleCAR T-Cell Therapy Development and Clinical Delivery
check_circleFounding Medical Director, Bezos Family Immunotherapy Clinic
check_circleHematopoietic Cell Transplantation Programme
check_circleRituximab Clinical Development
check_circleProfessor Emeritus, University of Washington – Division of Haematology & Oncology
check_circleAffiliate Investigator, Clinical Research Division, Fred Hutch
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Languages & International

Dr. Maloney conducts consultations in English.

πŸ‡ΊπŸ‡ΈEnglish
Interpreter Support Available

CancerFax can coordinate professional medical interpreter support for international patients consulting at Fred Hutchinson Cancer Center.

CancerFax can coordinate professional medical interpreter support for international patients requiring assistance in other languages.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. David Maloney

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. David Maloney's team β€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history β€” prepared as a structured clinical summary for Dr. David Maloney's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. David Maloney before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. David Maloney's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. David Maloney's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. David Maloney's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Dr. David Maloney

Dr. David G. Maloney is a physician-scientist and Professor Emeritus in the Translational Science and Therapeutics Division at Fred Hutchinson Cancer Center, Seattle. He is internationally recognised for his contributions to CAR T-cell therapy, monoclonal antibody therapy, and hematopoietic cell transplantation for blood cancers, including his instrumental role in the development and clinical testing of rituximab.

Dr. Maloney specialises in haematologic malignancies including lymphoma, non-Hodgkin lymphoma, chronic lymphocytic leukaemia, leukaemia, and multiple myeloma. He has particular expertise in cases where CAR T-cell therapy, cellular immunotherapy, or hematopoietic cell transplantation may be appropriate.

Fred Hutchinson Cancer Center provides patient support services for out-of-region and international patients. CancerFax can assist with coordinating report submission and consultation support. Because Dr. Maloney's current institutional role is listed as Professor Emeritus, patients should confirm his current appointment availability and clinical consultation options directly with Fred Hutch or through CancerFax.

Submit your medical reports through CancerFax using the Send Your Reports button. The CancerFax team will review the documentation, prepare a structured case summary, and coordinate the next steps with Fred Hutchinson Cancer Center, subject to availability and case acceptance.

A second-opinion request can be submitted through CancerFax with the patient's pathology reports, bone marrow biopsy results, molecular profiling, imaging, and prior treatment history. CancerFax will structure the case for submission to Fred Hutch. The final consultation format and timeline depend on the doctor's availability and institutional process.

Dr. Maloney helped develop and deliver CAR T-cell therapies at Fred Hutchinson Cancer Center and served as the founding medical director of the Bezos Family Immunotherapy Clinic, which is dedicated to cellular immunotherapy. He has led multiple clinical trials in CAR T-cell therapy for patients with leukaemia, lymphoma, and myeloma.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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