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Caicun Zhou
verifiedCancerFax Verified
schoolMD, PhD ยท Tongji University

Dr.ย Caicunย Zhou

MD, PhD

Professor & Director, Department of Oncology

corporate_fareShanghai Pulmonary Hospital, Tongji University

check_circleImmunotherapy
check_circleTargeted Therapy
check_circleLung Cancer & NSCLC
check_circleIASLC President 2025โ€“27
INSTITUTION
corporate_fareShanghai Pulmonary Hospital
DEPARTMENT
scienceDepartment of Oncology
SPECIALTY
medical_servicesLung Cancer ยท Immunotherapy ยท Targeted Therapy
LOCATION
location_onShanghai, China
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
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Caicun Zhou

MD, PhD

Prof. Caicun Zhou is one of China's most distinguished lung cancer oncologists and serves as Professor and Director of the Department of Oncology at Shanghai Pulmonary Hospital affiliated with Tongji University. He brings nearly 30 years of clinical experience to the diagnosis and systemic treatment of lung cancer, with expertise in early detection, targeted therapy, immunotherapy, and precision treatment planning.

Prof. Zhou completed visiting scientist training at MD Anderson Cancer Center in 2002 and earlier research training in Japan before building his career at Shanghai Pulmonary Hospital, one of China's major specialist centres for thoracic oncology. He has been involved in landmark clinical trials โ€” including OPTIMAL, HARMONi-2, and PAPILLON โ€” that have shaped international treatment standards for EGFR-mutated and PD-L1-positive non-small cell lung cancer. The official hospital profile reports that he has authored more than 300 papers, including over 100 SCI-indexed articles, and holds five national invention patents. In 2023, Prof. Zhou became the first expert from mainland China to be elected IASLC President-designate, and he serves as IASLC President for 2025โ€“2027. His team received the IASLC Cancer Care Team Award in 2022, recognised as the only Asian team among four global award winners that year.

workspace_premium30+Years Experience
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Visiting Days
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International Patient Coordination

CancerFax can coordinate medical-report review and consultation support for international patients seeking an opinion from Prof. Zhou at Shanghai Pulmonary Hospital, subject to hospital availability and case acceptance.

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Why Consider Prof. Caicun Zhou?

Prof. Zhou combines nearly 30 years of clinical expertise in lung cancer with global research leadership, making him one of the most sought-after oncologists for advanced NSCLC, EGFR-mutated lung cancer, and immunotherapy-based treatment.

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IASLC President 2025โ€“2027
First expert from mainland China elected as President of the International Association for the Study of Lung Cancer โ€” the world's leading lung cancer professional organisation.
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Landmark Trial Investigator
Key contributor to OPTIMAL, HARMONi-2, and PAPILLON โ€” pivotal trials that have redefined first-line treatment standards for EGFR-mutated and PD-L1-positive NSCLC internationally.
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Precision Lung Cancer Expertise
Nearly 30 years of specialised experience in targeted therapy, immunotherapy, anti-angiogenesis therapy, and individualised treatment planning for lung cancer, as stated by Shanghai Pulmonary Hospital.
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Internationally Recognised Research
More than 300 publications including over 100 SCI-indexed articles, with papers in The Lancet, The Lancet Oncology, New England Journal of Medicine, and Journal of Clinical Oncology.
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Areas of Specialization

Precision systemic oncology for lung cancer and NSCLC

Prof. Zhou's clinical practice is centred on modern precision oncology for lung cancer, matching treatment to molecular markers, tumour biology, and patient-specific needs.

Treatment Specialties

Immunotherapy

PD-1 and PD-L1 checkpoint inhibitor strategies for suitable lung cancer patients.

starsCheckpoint Inhibitor Therapy
  • arrow_rightPD-1 / PD-L1 inhibitors for PD-L1-positive NSCLC
  • arrow_rightImmunotherapy-based first-line treatment strategies
  • arrow_rightCombination immunotherapy and chemotherapy protocols
starsImmuno-Oncology Research Application
  • arrow_rightHARMONi-2 trial: ivonescimab vs pembrolizumab in PD-L1-positive advanced NSCLC
  • arrow_rightBiomarker-driven patient selection for immunotherapy

Targeted Therapy

Molecularly guided treatment for EGFR-mutated and driver-positive NSCLC.

starsEGFR-Targeted Therapy
  • arrow_rightEGFR TKIs for first-line and subsequent lines in EGFR-mutated NSCLC
  • arrow_rightOPTIMAL trial: erlotinib vs chemotherapy in EGFR mutation-positive NSCLC
  • arrow_rightManagement of EGFR exon 20 insertion mutations
starsAnti-Angiogenesis Therapy
  • arrow_rightAnti-angiogenic agents combined with systemic therapy for NSCLC
  • arrow_rightCombination strategies using anti-angiogenesis and targeted agents

Early Diagnosis & Comprehensive Treatment

Early-stage lung cancer detection and individualised multimodality management.

starsLung Cancer Early Diagnosis
  • arrow_rightEarly detection strategies for lung cancer
  • arrow_rightComprehensive staging and molecular profiling
  • arrow_rightIndividualised treatment planning based on stage and biology
starsComprehensive & Personalised Treatment
  • arrow_rightMultimodality treatment planning for advanced lung cancer
  • arrow_rightPersonalised therapy selection based on pathology and biomarkers
Clinical Focus Areas
check_circleNon-Small Cell Lung Cancer (NSCLC)
check_circleEGFR-Mutated Lung Cancer
check_circlePD-L1-Positive Advanced NSCLC
check_circleEGFR Exon 20 Insertion NSCLC
check_circleAdvanced & Metastatic Lung Cancer
check_circleThoracic Oncology
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Procedures Performed

Systemic and precision oncology services for lung cancer

Prof. Zhou's clinical services span the full lung cancer care pathway, from early diagnosis and molecular staging through first-line systemic therapy, resistance management, and clinical trial-based treatment.

Lung Cancer Medical Oncology

Medical Oncology

Comprehensive systemic treatment planning and administration for lung cancer, integrating chemotherapy, immunotherapy, and targeted therapy based on tumour biology.

Systemic Treatment Options
arrow_rightPlatinum-based chemotherapy for NSCLC
arrow_rightCheckpoint inhibitor immunotherapy for PD-L1-positive patients
arrow_rightAnti-angiogenesis therapy combined with systemic agents
arrow_rightIndividualised treatment planning and sequencing

Targeted Therapy for NSCLC

Targeted Therapy

Molecularly driven targeted treatment for driver-positive non-small cell lung cancer including EGFR-mutated and exon 20 insertion subtypes.

EGFR & Driver Mutation Treatment
arrow_rightEGFR TKI therapy for first-line and subsequent lines
arrow_rightAmivantamab plus chemotherapy for EGFR exon 20 insertion NSCLC (PAPILLON)
arrow_rightResistance mechanism evaluation and treatment adaptation

Comprehensive Staging & Diagnosis

Diagnosis

Thorough molecular and imaging evaluation to guide treatment selection for lung cancer patients.

Diagnostic Evaluation
arrow_rightEarly lung cancer detection and staging
arrow_rightMolecular profiling and biomarker testing (EGFR, PD-L1, ALK, ROS1)
arrow_rightTreatment pathway assessment based on pathology findings

Treatment Monitoring & Follow-Up

Monitoring

Ongoing assessment of treatment response and disease progression for lung cancer patients.

Response Assessment
arrow_rightImaging-based response evaluation during systemic therapy
arrow_rightToxicity monitoring and treatment modification
arrow_rightResistance assessment and next-line treatment planning

Second Opinion Consultations

Second Opinion

Expert independent review for patients with complex or advanced lung cancer seeking a specialist opinion.

Case Review Process
arrow_rightPathology, molecular profiling, and imaging review
arrow_rightAssessment of alternative treatment strategies
arrow_rightClinical trial eligibility evaluation
arrow_rightExpert written oncology opinion
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Research & Publications

International clinical trial leadership and peer-reviewed contributions

Prof. Zhou has published more than 300 papers including over 100 SCI-indexed articles across leading international journals, and has contributed to landmark lung cancer clinical trials that have influenced global treatment guidelines.

Key Publications
arrow_rightOPTIMAL: Erlotinib versus chemotherapy as first-line treatment for EGFR mutation-positive NSCLC โ€” The Lancet Oncology, 2011
arrow_rightPAPILLON: Amivantamab plus chemotherapy in NSCLC with EGFR exon 20 insertions โ€” New England Journal of Medicine, 2023
arrow_rightHARMONi-2: Ivonescimab versus pembrolizumab for PD-L1-positive advanced NSCLC โ€” The Lancet, 2024
arrow_rightMore than 300 total publications including 100+ SCI-indexed articles; also author of three books on lung cancer (IASLC)
Clinical Trial Contributions
arrow_rightOPTIMAL trial โ€” erlotinib vs chemotherapy in EGFR mutation-positive first-line NSCLC
arrow_rightPAPILLON phase III trial โ€” amivantamab plus chemotherapy in advanced NSCLC with EGFR exon 20 insertions
arrow_rightHARMONi-2 trial โ€” ivonescimab vs pembrolizumab in PD-L1-positive advanced NSCLC
Awards & Recognition
arrow_rightIASLC Cancer Care Team Award, 2022 โ€” only Asian team among four global award-winning teams
arrow_rightNational Science and Technology Progress Award, Second Prize
arrow_rightShanghai Science and Technology Progress Award, First Prize
arrow_rightState Council Special Allowance; Shanghai Leading Talent recognition
Extensive Research Profile

Prof. Zhou's full publication list is available via Google Scholar and PubMed. CancerFax can assist with sourcing relevant research publications on request.

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Education & Training

Prof. Zhou completed medical training in China and Japan, and undertook a visiting scientist fellowship at MD Anderson Cancer Center in the United States. His formal academic qualifications are MD and PhD. Specific undergraduate and postgraduate institutions were not publicly verified in accessible sources.

scheduleSpecific medical school and postgraduate training institutions are being verified. Core qualifications (MD, PhD) and visiting appointments are confirmed from authoritative sources.
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Clinical Experience

Prof. Zhou has built a career spanning nearly 30 years in lung cancer oncology, progressing from clinical roles at Bengbu Medical College to leading the Oncology Department at Shanghai Pulmonary Hospital, one of China's foremost specialist thoracic centres.

Professor & Director, Department of Oncology
Shanghai Pulmonary Hospital, Tongji University
Cancer Institute, Tongji University School of Medicine
check_circleDirector, Department of Oncology โ€” Shanghai Pulmonary Hospital
check_circleDirector, Cancer Institute โ€” Tongji University School of Medicine
check_circleChairman, Oncology Department โ€” Tongji University
check_circlePresident, IASLC 2025โ€“2027
check_circleFormer Associate Director โ€” Affiliated Hospital of Bengbu Medical College
check_circleChairman, CSCO Non-Small Cell Lung Cancer Committee
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Languages & International

Prof. Zhou consults in Chinese. English-language communication has not been formally verified from official sources.

๐Ÿ‡จ๐Ÿ‡ณChinese (Mandarin)
Interpreter Support Available

CancerFax provides professional medical interpreter support to facilitate consultations with Prof. Zhou for non-Chinese-speaking patients.

CancerFax can coordinate professional medical interpreter support for international patients consulting Prof. Zhou.

support_agentHow CancerFax Helps

How CancerFax Helps You Access Dr. Caicun Zhou

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Caicun Zhou's team โ€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history โ€” prepared as a structured clinical summary for Dr. Caicun Zhou's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Caicun Zhou before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Caicun Zhou's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Caicun Zhou's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Caicun Zhou's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Prof. Caicun Zhou

Prof. Zhou specialises in lung cancer, with particular focus on non-small cell lung cancer (NSCLC), advanced and metastatic NSCLC, EGFR-mutated NSCLC, EGFR exon 20 insertion NSCLC, and PD-L1-positive NSCLC. His clinical work also includes thoracic oncology more broadly.

Prof. Zhou is Director of the Department of Oncology at Shanghai Pulmonary Hospital affiliated with Tongji University in Shanghai, China โ€” one of China's leading specialist centres for lung disease and thoracic oncology.

Submit your medical reports through CancerFax using the Send Your Reports button. The CancerFax team will review the documents, prepare the case for submission, and coordinate the next steps with the hospital, subject to availability and case acceptance.

CancerFax can coordinate medical-report review and consultation support for international patients seeking an opinion from Prof. Zhou, subject to hospital availability and case acceptance. Please submit your reports through CancerFax to begin the process.

A second-opinion request can be submitted through CancerFax with the patient's pathology reports, imaging, molecular profiling results, treatment history, and relevant test results. The final consultation format and availability depend on the doctor's institution and scheduling.

Prof. Zhou's verified treatment expertise includes EGFR-targeted therapy, checkpoint inhibitor immunotherapy (PD-1 / PD-L1 inhibitors), anti-angiogenesis therapy, chemotherapy, and individualised comprehensive treatment planning. His approach is guided by molecular profiling and tumour biology, as highlighted by Shanghai Pulmonary Hospital.

Prof. Caicun Zhou was elected IASLC President-designate for 2023โ€“2025 and IASLC President for 2025โ€“2027, becoming the first expert from mainland China to hold this leadership role in the International Association for the Study of Lung Cancer. His team also received the IASLC Cancer Care Team Award in 2022, recognised as the only Asian team among four global winners that year.

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Connect with Caicun Zhou Today

Share your medical reports for a free preliminary review. Our patient coordinators will help you understand your options and arrange a direct consultation.

Free case review ยท No commitment ยท Response within 24 hours ยท Available in 12+ languages

Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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