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Anas Younes
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schoolMD, Hematologic Oncology

Dr.Β AnasΒ Younes

MD (Doctor of Medicine)

Chief, Lymphoma Service – Hematologic Oncology

corporate_fareMemorial Sloan Kettering Cancer Center, New York

check_circleHodgkin Lymphoma
check_circleCD30-Targeted Therapy
check_circleDLBCL & T-cell Lymphoma
check_circlePD-1 Checkpoint Inhibitors
INSTITUTION
corporate_fareMemorial Sloan Kettering Cancer Center
DEPARTMENT
scienceLymphoma Service, Division of Hematologic Oncology
SPECIALTY
medical_servicesLymphoma, CD30-Targeted Therapy, Immunotherapy
LOCATION
location_onNew York, NY, USA
INTERNATIONAL PATIENTS
publicInternational Patients Welcome
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Anas Younes

MD (Doctor of Medicine)

Dr. Anas Younes is one of the world's most recognised hematologic oncologists, with over 25 years of experience in lymphoma care, translational research, and novel drug development. He served as Chief of the Lymphoma Service at Memorial Sloan Kettering Cancer Center, one of the world's leading cancer hospitals, where he helped accelerate new treatment options for patients with Hodgkin and non-Hodgkin lymphoma.

Dr. Younes is internationally known for his pivotal role in the clinical development of brentuximab vedotin, a CD30-targeted antibody-drug conjugate that transformed the treatment of relapsed and refractory Hodgkin lymphoma and CD30-positive T-cell lymphoma. His research also helped establish PD-1 checkpoint inhibitors as a meaningful option in relapsed classical Hodgkin lymphoma. Before joining Memorial Sloan Kettering Cancer Center in 2013, he spent approximately two decades at The University of Texas MD Anderson Cancer Center, where he led clinical investigation and translational research programmes in lymphoma and myeloma. He is one of the most cited lymphoma oncologists worldwide and has served as principal investigator in numerous pivotal lymphoma trials. He currently holds a senior global hematology research and development leadership role at AstraZeneca, contributing to the next generation of blood cancer therapies.

workspace_premium25+Years Experience
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Visiting Days
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Why Consider Dr. Anas Younes?

Dr. Younes represents some of the most important advances in modern lymphoma treatment, with a career built on translational research, targeted therapy development, and expanding options for patients with difficult-to-treat lymphoma.

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Pioneer of CD30-Targeted Therapy
Dr. Younes played a major role in the clinical development of brentuximab vedotin, which became a landmark therapy for relapsed Hodgkin lymphoma and CD30-positive T-cell lymphoma. His work helped establish antibody-drug conjugates as a major treatment class in hematologic malignancies.
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25+ Years in Lymphoma Research and Clinical Care
With more than 25 years at leading institutions including MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center, Dr. Younes brings one of the deepest clinical and research backgrounds in lymphoma available internationally.
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Internationally Cited Lymphoma Expert
Dr. Younes is one of the most cited lymphoma oncologists worldwide. His clinical trial contributions and publications have shaped treatment guidelines and expanded options for patients with Hodgkin lymphoma, diffuse large B-cell lymphoma, and T-cell lymphoma.
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Arabic-Speaking and Accessible to International Patients
Dr. Younes consults in English and Arabic, making him directly accessible to patients from the Middle East, North Africa, and Arabic-speaking communities who require expert lymphoma guidance. CancerFax can support the coordination process for eligible cases.
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Areas of Specialisation

Expert lymphoma care with a focus on targeted therapy, immunotherapy, and novel agents for relapsed and refractory disease

Dr. Younes specialises in the full spectrum of lymphoid malignancies, with particular expertise in Hodgkin lymphoma, diffuse large B-cell lymphoma, T-cell lymphoma, and CD30-positive lymphomas. His clinical and research work integrates biomarker-driven treatment selection, antibody-drug conjugates, and immune checkpoint blockade.

Lymphoma Treatment Specialties

Hodgkin Lymphoma

Classical and nodular lymphocyte-predominant Hodgkin lymphoma, including relapsed and refractory disease after standard therapy or stem cell transplant.

starsRelapsed and Refractory Hodgkin Lymphoma
  • arrow_rightTreatment strategies for disease recurring after ABVD or escalated BEACOPP
  • arrow_rightEvaluation of options after autologous stem cell transplant failure
  • arrow_rightBrentuximab vedotin-based therapy for eligible patients
  • arrow_rightPD-1 inhibitor therapy for checkpoint-sensitive disease
starsCD30-Targeted and Biomarker-Directed Therapy
  • arrow_rightCD30 expression-guided treatment planning in Hodgkin lymphoma
  • arrow_rightAntibody-drug conjugate protocols for relapsed CD30-positive disease
  • arrow_rightCombination regimens incorporating targeted and immune agents

Non-Hodgkin Lymphoma

Diffuse large B-cell lymphoma, T-cell lymphoma, and other aggressive lymphoma subtypes, with emphasis on novel treatment strategies for patients who have relapsed or not responded to standard regimens.

starsDiffuse Large B-Cell Lymphoma (DLBCL)
  • arrow_rightNovel agent evaluation for relapsed or refractory DLBCL
  • arrow_rightBiomarker-directed treatment planning including molecular subtyping
  • arrow_rightClinical trial access and early-phase treatment options
starsT-Cell and CD30-Positive Lymphoma
  • arrow_rightSystemic anaplastic large cell lymphoma and peripheral T-cell lymphoma
  • arrow_rightCD30-targeted therapy including brentuximab vedotin
  • arrow_rightNovel combination approaches for aggressive T-cell subtypes

Immunotherapy and Novel Agents

Immune checkpoint inhibition, antibody-drug conjugates, and emerging targeted therapies in lymphoma, particularly for patients with limited options after multiple lines of treatment.

starsCheckpoint Inhibitor Therapy
  • arrow_rightPD-1 inhibitors including nivolumab and pembrolizumab in relapsed Hodgkin lymphoma
  • arrow_rightImmune-based treatment for PD-L1/PD-L2-expressing lymphoma subtypes
  • arrow_rightCombination immunotherapy strategies in appropriate clinical contexts
starsAntibody-Drug Conjugates
  • arrow_rightBrentuximab vedotin for CD30-positive Hodgkin and T-cell lymphoma
  • arrow_rightNext-generation ADC development and clinical investigation
Clinical Focus Areas
check_circleClassical Hodgkin Lymphoma
check_circleRelapsed and Refractory Lymphoma
check_circleDiffuse Large B-Cell Lymphoma
check_circleT-Cell Lymphoma
check_circleCD30-Positive Lymphomas
check_circleAntibody-Drug Conjugates
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Procedures and Clinical Services

Lymphoma diagnosis, targeted treatment planning, clinical trial access, and expert second opinion

Dr. Younes's clinical practice centres on the evaluation and management of complex and relapsed lymphoma, incorporating molecular diagnostics, novel targeted therapies, immunotherapy, and access to early-phase clinical investigations.

Lymphoma Diagnosis and Staging

Diagnosis

Comprehensive workup including biopsy evaluation, immunohistochemistry, molecular profiling, and staging assessment to guide precise treatment selection.

Diagnostic Services
arrow_rightPathology review and lymphoma subtype confirmation
arrow_rightCD30, PD-L1, and molecular marker assessment
arrow_rightPET-CT and imaging-based staging
arrow_rightBone marrow biopsy evaluation where indicated

Targeted and Immune-Based Therapy

Targeted Therapy

Molecularly guided treatment approaches incorporating CD30-targeted agents, checkpoint inhibitors, and next-generation lymphoma therapies.

Treatment Options
arrow_rightBrentuximab vedotin for CD30-positive Hodgkin and T-cell lymphoma
arrow_rightPD-1 checkpoint inhibitors for eligible relapsed classical Hodgkin lymphoma
arrow_rightCombination targeted and immune-based regimens
arrow_rightBiomarker-directed treatment planning

Systemic Lymphoma Treatment

Medical Oncology

Medical management of Hodgkin lymphoma, diffuse large B-cell lymphoma, T-cell lymphoma, and related hematologic malignancies.

Medical Oncology Services
arrow_rightFrontline and salvage chemotherapy protocols
arrow_rightConsolidation and maintenance therapy planning
arrow_rightResponse assessment and treatment adaptation
arrow_rightToxicity management and supportive care coordination

Second Opinion and Complex Lymphoma Review

Second Opinion

Expert review of complex, relapsed, or refractory lymphoma cases, providing an independent clinical perspective on diagnosis, staging, and treatment strategy.

Second Opinion Services
arrow_rightIndependent pathology and staging review
arrow_rightTreatment strategy evaluation for relapsed or refractory disease
arrow_rightAssessment of clinical trial eligibility
arrow_rightCoordination through CancerFax for international cases
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Research and Publications

Landmark contributions to lymphoma drug development, antibody-drug conjugates, and checkpoint immunotherapy

Dr. Younes is one of the most cited lymphoma oncologists internationally, with a research career spanning targeted therapy, immune checkpoint blockade, antibody-drug conjugates, and biomarker-guided treatment strategies. His work has directly influenced the treatment of Hodgkin lymphoma, DLBCL, and T-cell lymphoma.

Antibody-Drug Conjugates and CD30-Targeted Therapy
arrow_rightBrentuximab vedotin (SGN-35) for relapsed or refractory CD30-positive lymphomas – New England Journal of Medicine, 2010
arrow_rightPhase I clinical trial of brentuximab vedotin in Hodgkin lymphoma and systemic anaplastic large-cell lymphoma – Journal of Clinical Oncology, 2012
arrow_rightMultiple peer-reviewed publications on CD30-targeted antibody-drug conjugate mechanisms, efficacy, and clinical outcomes in lymphoma
PD-1 Checkpoint Inhibition in Hodgkin Lymphoma
arrow_rightNivolumab for relapsed or refractory classical Hodgkin lymphoma after autologous hematopoietic-cell transplantation – New England Journal of Medicine, 2016
arrow_rightPembrolizumab in relapsed or refractory classical Hodgkin lymphoma – Journal of Clinical Oncology, 2016
arrow_rightContributions to pivotal studies establishing checkpoint inhibitors as standard of care for multiply relapsed classical Hodgkin lymphoma
Novel Agents in DLBCL and T-Cell Lymphoma
arrow_rightResearch on novel combination strategies for relapsed or refractory diffuse large B-cell lymphoma
arrow_rightEarly-phase and pivotal trial contributions in peripheral T-cell lymphoma and other aggressive lymphoma subtypes
arrow_rightBiomarker-driven treatment selection in aggressive non-Hodgkin lymphoma – multiple publications across major hematology journals
Clinical Trial Leadership
arrow_rightPrincipal investigator in pivotal brentuximab vedotin registration trials for Hodgkin lymphoma and systemic ALCL
arrow_rightPrincipal or major investigator in nivolumab and pembrolizumab clinical trials in classical Hodgkin lymphoma
arrow_rightLeadership roles in early-phase lymphoma trials at MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center
Full Publication Record

Dr. Younes's complete publication list is available on PubMed and Google Scholar. He is among the most cited lymphoma oncologists in the world, with contributions spanning more than two decades of lymphoma drug development.

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Education & Training

Dr. Younes received his medical training in Syria before completing residency and fellowship training in the United States, including haematology-oncology fellowship at Memorial Sloan Kettering Cancer Center.

Medical Degree
MD
University of Damascus School of Medicine, Syria
1980s
Medical degree from the University of Damascus, laying the foundation for his subsequent training in haematology and oncology in the United States.
Residency
Residency – Internal Medicine
United States (institution to be confirmed)
Late 1980s – Early 1990s
Internal medicine residency completed in the United States following medical graduation.
Fellowship
Fellowship – Haematology-Oncology
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Early 1990s
Specialised haematology-oncology training at Memorial Sloan Kettering Cancer Center, one of the world's premier cancer institutions, providing the clinical and research foundation for his subsequent lymphoma career.
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Clinical Experience

Dr. Younes has held senior clinical and research leadership positions at two of the world's most prominent cancer centres, spanning more than 25 years of dedicated lymphoma practice and drug development.

Senior Vice President, Global Head of Haematology R&D
AstraZeneca
Global Haematology Research and Development
check_circleHodgkin and non-Hodgkin lymphoma clinical research
check_circleAntibody-drug conjugate development and CD30-targeted therapy
check_circlePD-1 checkpoint inhibitor trials in Hodgkin lymphoma
check_circleBiomarker-guided and precision lymphoma treatment
check_circleEarly-phase and pivotal clinical trial leadership
check_circleGlobal haematology drug development and medical leadership
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Languages & International

Dr. Anas Younes consults in the following languages.

πŸ‡¬πŸ‡§English
πŸ‡ΈπŸ‡¦Arabic
Arabic-Speaking Oncologist

Dr. Younes consults in both English and Arabic, making him directly accessible to patients from the Middle East, North Africa, and Arabic-speaking communities seeking expert lymphoma care at Memorial Sloan Kettering Cancer Center.

CancerFax can coordinate professional medical interpreter support for patients consulting in other languages.

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How CancerFax Helps You Access Dr. Anas Younes

CancerFax is a specialist cancer patient-navigation platform. We help international patients prepare structured medical summaries, assess treatment eligibility, and connect directly with Dr. Anas Younes's team β€” with full coordination from initial inquiry to consultation.

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Medical Report Review

Free review of your pathology results, imaging, molecular profiling, and treatment history β€” prepared as a structured clinical summary for Dr. Anas Younes's team.

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Treatment Eligibility Screening

CancerFax screens your case for eligibility for treatments and clinical programmes available through Dr. Anas Younes before you travel, so you arrive with a clear pathway.

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Case Submission

We coordinate direct case submission to Dr. Anas Younes's department, including all documentation required for clinical review and appointment scheduling.

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Appointment & Consultation Coordination

CancerFax manages appointment scheduling with Dr. Anas Younes's team, confirming availability and aligning timelines with your travel plans.

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Travel, Visa & Logistics Support

We prepare visa invitation letters, provide hospital-proximity accommodation guidance, and coordinate airport transfers for international patients.

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Follow-Up & Continuity of Care

After your consultation or treatment, CancerFax facilitates communication between Dr. Anas Younes's team and your home oncologist for seamless post-treatment follow-up.

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Frequently Asked Questions About Dr. Anas Younes

Dr. Anas Younes is an internationally recognised hematologic oncologist and lymphoma researcher with over 25 years of experience. He is best known for his pivotal role in the clinical development of brentuximab vedotin, a CD30-targeted antibody-drug conjugate, and for his contributions to PD-1 checkpoint inhibitor research in relapsed classical Hodgkin lymphoma. He formerly served as Chief of the Lymphoma Service at Memorial Sloan Kettering Cancer Center in New York.

Dr. Younes specialises in lymphoid malignancies, with primary expertise in classical Hodgkin lymphoma, diffuse large B-cell lymphoma, T-cell lymphoma, and CD30-positive lymphomas including systemic anaplastic large-cell lymphoma. His research and clinical focus are especially relevant for patients with relapsed or refractory disease who require targeted or immune-based therapy.

A second-opinion request can be submitted through CancerFax with the patient's complete pathology reports, imaging, treatment history, and relevant laboratory results. The CancerFax team will review the documents and coordinate the case submission to Memorial Sloan Kettering Cancer Center. The consultation format and timeline depend on the doctor's availability and hospital acceptance criteria.

Memorial Sloan Kettering Cancer Center has an established international patient programme. CancerFax can coordinate the process for international patients seeking a review or consultation, including case preparation, report translation support, and communication with the hospital's international team. Acceptance is subject to case suitability and the hospital's availability.

Brentuximab vedotin is an antibody-drug conjugate that targets the CD30 protein expressed in classical Hodgkin lymphoma and some T-cell lymphomas. Dr. Younes played a central role in the clinical development of this therapy, including leading or contributing to pivotal clinical trials that led to its approval. Brentuximab vedotin is now a standard treatment option for relapsed or refractory CD30-positive lymphoma.

Yes. Dr. Anas Younes consults in both English and Arabic. This makes him directly accessible to patients from the Middle East, North Africa, and other Arabic-speaking communities who are seeking expert lymphoma guidance or a second opinion from one of the world's leading lymphoma specialists.

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Medical Disclaimer: Information on this page is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making any medical decisions.

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